Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.60 |
| ▸ | RAB9A | P51151 | 7/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bumetrizole SCHEMBL8603228 | 0.96 | NPC1 (0.53) | NPC1RAB9APOLBLMNAALDH1A1 | |
| Bumetrizole SCHEMBL8054070 | 0.96 | NPC1 (0.53) | NPC1RAB9APOLBLMNAALDH1A1 | |
| Bumetrizole SCHEMBL2398487 | 0.96 | NPC1 (0.53) | NPC1RAB9APOLBLMNAALDH1A1 | |
| Bumetrizole SCHEMBL23734 | 0.96 | NPC1 (0.53) | NPC1RAB9APOLBLMNAALDH1A1 | |
| Bumetrizole SCHEMBL8056551 | 0.96 | NPC1 (0.53) | NPC1RAB9APOLBLMNAALDH1A1 | |
| Bumetrizole SCHEMBL29353083 | 0.96 | NPC1 (0.53) | NPC1RAB9APOLBLMNAALDH1A1 | |
| Bumetrizole SCHEMBL10836210 | 0.95 | NPC1 (0.52) | NPC1RAB9APOLBLMNAALDH1A1 | |
| Bumetrizole SCHEMBL6029618 | 0.95 | NPC1 (0.52) | NPC1RAB9APOLBLMNAALDH1A1 | |
| Bumetrizole SCHEMBL9273939 | 0.95 | NPC1 (0.52) | NPC1RAB9APOLBLMNAALDH1A1 | |
| Bumetrizole SCHEMBL9301984 | 0.95 | NPC1 (0.52) | NPC1RAB9APOLBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006090911-A1 | CELLULOSE ESTER FILM, POLARIZING PLATE AND LIQUID-CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2006-08-31 | — | — | WO | disclosed |