SCHEMBL12200552

SCHEMBL12200552

C=CC(=O)NCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ZDHHC20 Q5W0Z9 1/20 0.40
ZDHHC2 Q9UIJ5 1/20 0.40
GAA P10253 1/20 0.33
CA2 P00918 1/20 0.32
GBA1 P04062 3/20 0.32
THRB P10828 1/20 0.31
TGM2 P21980 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12200555 0.98 ALDH1A1 (0.42) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL12200581 0.89 ZDHHC20 (0.47) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL12200559 0.87 ZDHHC20 (0.50) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL12200576 0.82 ALDH1A1 (0.43) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL20826714 0.81 ALDH1A1 (0.36) ALDH1A1TSHRMAPK1TDP1TGM2
SCHEMBL13146836 0.80 ALDH1A1 (0.45) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL20826612 0.79 ALDH1A1 (0.37) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL8765966 0.77 ALDH1A1 (0.50) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL13827121 0.77 GBA1 (0.33) ALDH1A1CA2GBA1THRB
SCHEMBL17192467 0.76 MEN1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226814-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed
US-20110242654-A1 Hardcoat layer-forming composition, optical film, production method of optical film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2011-10-06 US disclosed