SCHEMBL12200560

SCHEMBL12200560

C=C(C)C(=O)NCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.41
THRB P10828 1/20 0.32
TGFBR1 P36897 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13146825 0.98 CA2 (0.39) CA2TGFBR1
SCHEMBL16443268 0.93 CA2 (0.34) CA2TGFBR1
SCHEMBL13862863 0.93 TGFBR1 (0.33) CA2TGFBR1
SCHEMBL16443433 0.85 TGFBR1 (0.33) TGFBR1
SCHEMBL13862886 0.85 TGFBR1 (0.35) TGFBR1
SCHEMBL12199962 0.83 CA2 (0.31) CA2THRB
SCHEMBL2998940 0.83 CA2 (0.31) CA2THRB
SCHEMBL12199997 0.81 GBA1 (0.30)
SCHEMBL16443543 0.79 GAA (0.34) TGFBR1
SCHEMBL12200553 0.79 GBA1 (0.36) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226814-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed
US-20110242654-A1 Hardcoat layer-forming composition, optical film, production method of optical film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2011-10-06 US disclosed
US-7799242-B2 Liquid crystalline composition, optically anisotropic film, optical film, and polarizer and liquid-crystal display device using them FUJIFILM CORPORATION (JP) 2010-09-21 US disclosed
US-20080225210-A1 Optical Compensation Film, Polarizing Plate, and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-09-18 US disclosed
US-20080203357-A1 Liquid Crystalline Composition, Optically Anisotropic Film, Optical Film, and Polarizer and Liquid-Crystal Display Device Using Them FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed