Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRND | Q07001 | 6/20 | 0.59 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.59 |
| ▸ | CHRNG | P07510 | 2/20 | 0.59 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.59 |
| ▸ | GRIA1 | P42261 | 8/20 | 0.58 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.56 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.56 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.56 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.56 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13827705 | 0.87 | GRIA1 (0.65) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL4147882 | 0.84 | NAALAD2 (0.61) | GRIA1 | |
| SCHEMBL4147877 | 0.84 | NAALAD2 (0.61) | GRIA1 | |
| SCHEMBL5007773 | 0.83 | GRIA1 (0.62) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL5009890 | 0.83 | GRIA1 (0.62) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL30081065 | 0.81 | ACE (0.56) | GRIA1 | |
| SCHEMBL29352083 | 0.81 | ALDH1A1 (0.50) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL21466071 | 0.81 | ALDH1A1 (0.50) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL30081063 | 0.81 | ACE (0.56) | GRIA1 | |
| SCHEMBL4152603 | 0.81 | MDM4 (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034365-B2 | Polymer substituted with amide or thioamide groups; vascular stents, bioreabsorbable polymers | REVA MEDICAL, INC. (US) | 2011-10-11 | — | — | US | disclosed |
| US-20080112999-A1 | N-SUBSTITUTED MONOMERS AND POLYMERS | REVA MEDICAL, INC. (US) | 2008-05-15 | — | — | US | disclosed |