Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | MDM4 | O15151 | 1/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | CHRND | Q07001 | 6/20 | 0.47 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.47 |
| ▸ | CHRNG | P07510 | 2/20 | 0.47 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.47 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29352083 | 1.00 | ALDH1A1 (0.50) | ALDH1A1NPSR1BACE1MDM4MDM2 | |
| Bicarbonate SCHEMBL30452528 | 0.97 | MDM4 (0.51) | ALDH1A1NPSR1BACE1MDM4MDM2 | |
| SCHEMBL3929918 | 0.95 | ALDH1A1 (0.57) | ALDH1A1BACE1MDM4MDM2GRIA1 | |
| SCHEMBL12009639 | 0.95 | ALDH1A1 (0.57) | ALDH1A1BACE1MDM4MDM2GRIA1 | |
| SCHEMBL29349987 | 0.91 | ALDH1A1 (0.46) | ALDH1A1NPSR1BACE1MDM4MDM2 | |
| SCHEMBL14049475 | 0.91 | ALDH1A1 (0.44) | ALDH1A1NPSR1BACE1MDM4MDM2 | |
| SCHEMBL23864850 | 0.90 | ALDH1A1 (0.47) | ALDH1A1NPSR1BACE1MDM4MDM2 | |
| SCHEMBL13123764 | 0.90 | ALDH1A1 (0.48) | ALDH1A1NPSR1BACE1MDM4MDM2 | |
| SCHEMBL21884113 | 0.90 | ALDH1A1 (0.46) | ALDH1A1NPSR1BACE1MDM4MDM2 | |
| SCHEMBL31072235 | 0.90 | ALDH1A1 (0.48) | ALDH1A1NPSR1BACE1MDM4MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3635029-B1 | SYNTHESIS OF TYROSINE DERIVED POLYARYLATES | MEDTRONIC INC (US) | 2021-03-17 | — | — | EP | claimed |
| EP-3312155-B1 | POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES | UNIV RUTGERS (US) | 2020-08-05 | — | — | EP | claimed |
| US-11359050-B2 | Synthesis of tyrosine derived polyarylates | MEDTRONIC, INC. (US) | 2022-06-14 | — | — | US | disclosed |
| US-20200354514-A1 | SYNTHESIS OF TYROSINE DERIVED POLYARYLATES | MEDTRONIC, INC. (US) | 2020-11-12 | — | — | US | disclosed |
| US-10793670-B2 | Synthesis of tyrosine derived polyarylates | MEDTRONIC, INC. (US) | 2020-10-06 | — | — | US | disclosed |
| US-20200171214-A1 | BIORESORBABLE SURFACE COATING FOR DELAYING DEGRADATION | DREI LILIEN PVG GMBH & CO. KG (DE) | 2020-06-04 | — | — | US | disclosed |
| US-10442757-B2 | Synthesis of tyrosine derived diphenol monomers | MEDTRONIC, INC. (US) | 2019-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10442757-B2 | Synthesis of tyrosine derived diphenol monomers | TYR, TH, TYRO3 | ALDH1A1 1997/4885NPSR1 3757/4885BACE1 4661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.