Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14499884 | 0.83 | NPC1 (0.61) | NPC1MAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL20127259 | 0.82 | CA1 (0.58) | NPC1MAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11985689 | 0.82 | MAPT (0.73) | NPC1MAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16590828 | 0.79 | MAPT (0.55) | NPC1MAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL27824110 | 0.79 | SMN1; SMN2 (0.64) | NPC1MAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14947133 | 0.78 | NPC1 (0.50) | NPC1MAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16704815 | 0.78 | MAPT (0.60) | NPC1MAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL27881866 | 0.78 | MAPT (0.60) | NPC1MAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL20443618 | 0.78 | ESR2 (0.77) | NPC1MAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL206554 | 0.78 | TDP1 (0.61) | NPC1MAPTRAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034125-B2 | Dye composition comprising at least one colorless disulfide/thiol precursor, and dyeing process using the composition | L'OREAL S.A. (FR) | 2011-10-11 | — | — | US | disclosed |
| US-20110016642-A1 | DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION | L'OREAL S.A. (FR) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110016642-A1 | DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION | KRT18, SQOR, TST | NPC1 4859/4885MAPT 1485/4885RAB9A 4130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.