Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | JUN | P05412 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17226936 | 1.00 | L3MBTL1 (0.41) | L3MBTL1MGLLPPARGPPARALMNA | |
| SCHEMBL12202398 | 0.94 | MGLL (0.40) | L3MBTL1MGLLPPARGPPARALMNA | |
| SCHEMBL12203684 | 0.94 | MGLL (0.40) | L3MBTL1MGLLPPARGPPARALMNA | |
| SCHEMBL2476675 | 0.88 | MGLL (0.41) | L3MBTL1MGLLLMNAMAOBCYP3A4 | |
| SCHEMBL10151369 | 0.88 | MGLL (0.41) | L3MBTL1MGLLLMNAMAOBCYP3A4 | |
| SCHEMBL10151059 | 0.87 | MGLL (0.41) | MGLLLMNAALDH1A1GAAMAOB | |
| SCHEMBL2477015 | 0.87 | MGLL (0.41) | MGLLLMNAALDH1A1GAAMAOB | |
| SCHEMBL6742294 | 0.87 | MGLL (0.41) | MGLLLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL13263786 | 0.87 | MGLL (0.41) | MGLLLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL2481304 | 0.86 | MGLL (0.40) | MGLLALDH1A1MAOBCYP3A4ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374794-A1 | CYCLIC AMINE COMPOUNDS | Daiichi Sankyo Company, Limited (JP) | 2011-10-12 | — | — | EP | disclosed |