Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14556006 | 0.86 | MGAM (0.39) | THRBMGAMLMNATDP1 | |
| SCHEMBL14668783 | 0.83 | LMNA (0.50) | MGAMLMNAL3MBTL1TDP1 | |
| SCHEMBL14555945 | 0.83 | LMNA (0.50) | MGAMLMNAL3MBTL1TDP1 | |
| SCHEMBL11148560 | 0.83 | LMNA (0.50) | MGAMLMNAL3MBTL1TDP1 | |
| SCHEMBL17168356 | 0.83 | LMNA (0.50) | MGAMLMNAL3MBTL1TDP1 | |
| SCHEMBL23017513 | 0.83 | LMNA (0.50) | MGAMLMNAL3MBTL1TDP1 | |
| SCHEMBL12608467 | 0.83 | LMNA (0.50) | MGAMLMNAL3MBTL1TDP1 | |
| SCHEMBL14176473 | 0.83 | LMNA (0.50) | MGAMLMNAL3MBTL1TDP1 | |
| SCHEMBL7256974 | 0.80 | TDP1 (0.37) | MGAMLMNAL3MBTL1TDP1 | |
| SCHEMBL4941872 | 0.80 | TDP1 (0.37) | MGAMLMNAL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2377528-A2 | Fatty acid metabolism inhibitors for use in the treatment of cancer | The Board of Regents of the University of Colorado (US) | 2011-10-19 | — | — | EP | disclosed |