Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.47 |
| ▸ | MGAM | O43451 | 5/20 | 0.47 |
| ▸ | AMY1A | P0DUB6 | 5/20 | 0.47 |
| ▸ | SI | P14410 | 5/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.47 |
| ▸ | F12 | P00748 | 4/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10103354 | 0.70 | SMN1; SMN2 (0.48) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL29193567 | 0.67 | SMN1; SMN2 (0.47) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL2095767 | 0.67 | KDM4E (0.59) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL12167112 | 0.67 | KCNMA1 (0.42) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL28678482 | 0.66 | HDAC3 (0.55) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL21021687 | 0.66 | GAA (0.40) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL2395074 | 0.66 | KCNMA1 (0.49) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL15237507 | 0.65 | KCNMA1 (0.52) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL20676399 | 0.65 | KCNMA1 (0.43) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL18239427 | 0.65 | MGAM (0.44) | GAAMGAMAMY1ASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374794-A1 | CYCLIC AMINE COMPOUNDS | Daiichi Sankyo Company, Limited (JP) | 2011-10-12 | — | — | EP | disclosed |