Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Pyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.30 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL11617873 | 1.00 | NAPRT (0.56) | NAPRTTSHRTDP1CA5ACA5B | |
| Pyridine SCHEMBL122023 | 1.00 | NAPRT (0.56) | NAPRTTSHRTDP1CA5ACA5B | |
| Pyridine SCHEMBL1005857 | 0.97 | NAPRT (0.60) | NAPRTTSHRTDP1CA5ACA5B | |
| Pyridine SCHEMBL22261964 | 0.97 | NAPRT (0.60) | NAPRTTSHRTDP1CA5ACA5B | |
| Pyridine SCHEMBL22261990 | 0.97 | NAPRT (0.60) | NAPRTTSHRTDP1CA5ACA5B | |
| Pyridine SCHEMBL407438 | 0.97 | NAPRT (0.60) | NAPRTTSHRTDP1CA5ACA5B | |
| Pyridine SCHEMBL1407986 | 0.97 | NAPRT (0.60) | NAPRTTSHRTDP1CA5ACA5B | |
| Pyridine SCHEMBL3316655 | 0.97 | NAPRT (0.60) | NAPRTTSHRTDP1CA5ACA5B | |
| Pyridine SCHEMBL25405557 | 0.94 | NAPRT (0.56) | NAPRTTSHRTDP1CA5ACA5B | |
| Pyridine SCHEMBL22151317 | 0.94 | NAPRT (0.56) | NAPRTTSHRTDP1CA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240279509-A1 | WATER-BASED RADIATION-CURABLE COMPOSITION FOR SOFT FEEL APPLICATIONS | ALLNEX USA INC. (US) | 2024-08-22 | — | — | US | disclosed |
| EP-4363469-A1 | WATER-BASED RADIATION-CURABLE COMPOSITION FOR SOFT FEEL APPLICATIONS | Allnex USA Inc. (US) | 2024-05-08 | — | — | EP | disclosed |
| CN-117580880-A | Water-based radiation curable compositions for soft feel applications | 湛新美国股份有限公司 | 2024-02-20 | — | — | CN | disclosed |
| EP-3519493-B1 | RADIATION CURABLE COMPOSITIONS WITH ANTI-STAIN PROPERTIES | ALLNEX Belgium SA (BE) | 2023-08-09 | — | — | EP | disclosed |
| WO-2023278118-A1 | WATER-BASED RADIATION-CURABLE COMPOSITION FOR SOFT FEEL APPLICATIONS | ALLNEX USA INC. (US) | 2023-01-05 | — | — | WO | disclosed |
| EP-3681922-B1 | RADIATION CURABLE AQUEOUS COMPOSITIONS | ALLNEX Belgium SA (BE) | 2022-12-07 | — | — | EP | disclosed |
| US-11485817-B2 | Radiation curable aqueous compositions | ALLNEX BELGIUM S.A. (BE) | 2022-11-01 | — | — | US | disclosed |
| EP-2945973-B2 | RADIATION CURABLE AQUEOUS COMPOSITIONS WITH REVERSIBLE DRYING | ALLNEX Belgium SA (BE) | 2022-09-21 | — | — | EP | disclosed |
| US-11359110-B2 | Radiation curable compositions with anti-stain properties | ALLNEX BELGIUM S.A. (BE) | 2022-06-14 | — | — | US | disclosed |
| CN-109844004-B | Radiation curable compositions having antifouling properties | 湛新比利时股份有限公司 | 2021-11-30 | — | — | CN | disclosed |
| EP-2288638-A1 | AQUEOUS RADIATION CURABLE POLYURETHANE COMPOSITIONS | Cytec Surface Specialties, S.A. (BE) | 2011-03-02 | — | — | EP | disclosed |
| WO-2010003924-A1 | AQUEOUS RADIATION CURABLE POLYURETHANE COMPOSITIONS | CYTEC SURFACE SPECIALTIES, S.A. (BE) | 2010-01-14 | — | — | WO | disclosed |
| EP-2143748-A1 | Aqueous radiation curable polyurethane compositions | CYTEC SURFACE SPECIALTIES, S.A. (BE) | 2010-01-13 | — | — | EP | disclosed |
| WO-2009147092-A1 | AQUEOUS RADIATION CURABLE POLYURETHANE COMPOSITIONS | CYTEC SURFACE SPECIALTIES, S.A. (BE) | 2009-12-10 | — | — | WO | disclosed |
| EP-2130846-A1 | Aqueous radiation curable polyurethane compositions | Cytec Surface Specialties, S.A. (BE) | 2009-12-09 | — | — | EP | disclosed |
| US-20090270581-A1 | Aqueous Radiation Curable Polyurethane Compositions | ALLNEX BELGIUM S.A. (BE) | 2009-10-29 | — | — | US | disclosed |
| EP-2013302-A1 | AQUEOUS RADIATION CURABLE POLYURETHANE COMPOSITIONS | CYTEC SURFACE SPECIALTIES, S.A. (BE) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007118781-A1 | AQUEOUS RADIATION CURABLE POLYURETHANE COMPOSITIONS | CYTEC SURFACE SPECIALTIES, S.A. (BE) | 2007-10-25 | — | — | WO | disclosed |
| EP-1845143-A1 | Aqueous radiation curable polyurethane compositions | CYTEC SURFACE SPECIALTIES, S.A. (BE) | 2007-10-17 | — | — | EP | disclosed |
| US-4212518-A | ELECTROCHROMIC CELL | CANON KABUSHIKI KAISHA (JP) | 1980-07-15 | — | — | US | disclosed |