Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Pyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.31 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL22261990 | 1.00 | NAPRT (0.60) | NAPRTTSHRTDP1CA5ACA5B | |
| Pyridine SCHEMBL1005857 | 1.00 | NAPRT (0.60) | NAPRTTSHRTDP1CA5ACA5B | |
| Pyridine SCHEMBL22261964 | 1.00 | NAPRT (0.60) | NAPRTTSHRTDP1CA5ACA5B | |
| Pyridine SCHEMBL1407986 | 1.00 | NAPRT (0.60) | NAPRTTSHRTDP1CA5ACA5B | |
| Pyridine SCHEMBL3316655 | 1.00 | NAPRT (0.60) | NAPRTTSHRTDP1CA5ACA5B | |
| Pyridine SCHEMBL25405557 | 0.97 | NAPRT (0.56) | NAPRTTSHRTDP1CA5ACA5B | |
| Pyridine SCHEMBL22151317 | 0.97 | NAPRT (0.56) | NAPRTTSHRTDP1CA5ACA5B | |
| Pyridine SCHEMBL22151316 | 0.97 | NAPRT (0.56) | NAPRTTSHRTDP1CA5ACA5B | |
| Pyridine SCHEMBL122022 | 0.97 | NAPRT (0.56) | NAPRTTSHRTDP1CA5ACA5B | |
| Pyridine SCHEMBL11617873 | 0.97 | NAPRT (0.56) | NAPRTTSHRTDP1CA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025245379-A1 | SUPERCRITICAL FLUIDS REGENERATION OF PFAS-CONTAMINATED SPENT MEDIA AND WATER TREATMENT TRAIN | UNIVERSITY OF WASHINGTON (US) | 2025-11-27 | — | — | WO | claimed |
| EP-3822259-B1 | METHOD FOR SYNTHESIZING VALSARTAN | ZHEJIANG HUAHAI PHARM CO LTD (CN) | 2025-08-27 | — | — | EP | claimed |
| US-20250207049-A1 | METHOD FOR PRETREATING WASTE FAT, OIL AND GREASE AND CO-PRODUCING FIRST-GENERATION BIODIESEL | FUZHOU UNIVERSITY (CN) | 2025-06-26 | — | — | US | claimed |
| US-20250051311-A1 | Method for Preparing High-Purity Losartan | ZHEJIANG HUAHAI PHARMACEUTICAL CO., LTD. (CN) | 2025-02-13 | — | — | US | claimed |
| US-12180181-B1 | 4-[4,5-bis(4-bromophenyl)-1-hexyl-1H-imidazol-2-yl]isoquinolin-3-ol as an antimicrobial compound | King Faisal University (SA) | 2024-12-31 | — | — | US | claimed |
| CN-119175052-A | Industrial preparation method of acrolein | 中国石油化工股份有限公司 | 2024-12-24 | — | — | CN | claimed |
| US-12162839-B1 | 4,5-bis(4-bromophenyl)-2-(4-bromophenyl)-1-hexyl-1H-imidazole as an antimicrobial compound | King Faisal University (SA) | 2024-12-10 | — | — | US | claimed |
| CN-119019307-A | Vitamin D3Is prepared by the preparation method of (2) | 厦门金达威维生素有限公司 | 2024-11-26 | — | — | CN | claimed |
| CN-118634644-B | Acrylic ester tail gas treatment method | 江苏环保产业技术研究院股份公司 | 2024-11-08 | — | — | CN | claimed |
| US-12134604-B1 | 1-[4,5-bis(4-chlorophenyl)-1-hexyl-1H-imidazol-2-yl]-2-naphthol as an antimicrobial compound | King Faisal University (SA) | 2024-11-05 | — | — | US | claimed |
| EP-0411541-A2 | Process for preparing monobactames and their intermediate product | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1991-02-06 | — | — | EP | claimed |
| EP-0107860-B1 | PEPTIDES, PROCESS FOR PREPARING THE SAME AND PSYCHODEPRESSANT COMPOSITIONS CONTAINING THE SAME | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1986-09-17 | — | — | EP | claimed |
| US-4565811-A | Sodium salt of ursodeoxycholic sulphate | ISTITUTO BIOLOGICO CHEMIOTERAPICO "ABC" S.P.A. (IT) | 1986-01-21 | — | — | US | claimed |
| EP-0159026-A2 | Pentaerythritol derivatives and a process for preparing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1985-10-23 | — | — | EP | claimed |
| EP-0117570-A1 | Sodium salt of ursodeoxycholic sulphate | ISTITUTO BIOLOGICO CHEMIOTERAPICO "ABC" S.p.A. (IT) | 1984-09-05 | — | — | EP | claimed |
| EP-0107860-A1 | Peptides, process for preparing the same and psychodepressant compositions containing the same | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1984-05-09 | — | — | EP | claimed |
| EP-0053387-A1 | Method of preparing 1-sulfo-2-oxoazetidine derivatives and intermediates therefor | Takeda Chemical Industries, Ltd. (JP) | 1982-06-09 | — | — | EP | claimed |
| US-4269992-A | REFLUXING A POLYDIHYDROCARBON SILOXANE CONTAINING HALOGEN GROUPS AND AN ALCOHOL-MODIFIED POLYOXYALKYLENE GLYCOL IN A SOLVENT OF AN ALKYL OR ALKENYL HALIDE | UNION CARBIDE CORPORATION (US) | 1981-05-26 | — | — | US | claimed |
| US-4093522-A | WITH WATER SOLUBLE PYRIDINIUM, QUINOLINIUM OR ACRIDINIUM SULFATE AND HALIDE | DILLENBERG HORST | 1978-06-06 | — | — | US | claimed |
| US-4067825-A | Method for preparation of amphoteric ion-exchangers by substitution of hydrophilic polymers | CESKOSLOVENSKA AKADEMIE VED (CS) | 1978-01-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051311-A1 | Method for Preparing High-Purity Losartan | AGTR1, AGTR2, AGT | NAPRT 1355/4885TSHR 1906/4885TDP1 1715/4885 |
| US-12134604-B1 | 1-[4,5-bis(4-chlorophenyl)-1-hexyl-1H-imidazol-2-yl]-2-naphthol as an antimicrobial compound | NOC2L, NCKAP1L, NOM1 | NAPRT 372/4885TSHR 4524/4885TDP1 3458/4885 |
| US-12180181-B1 | 4-[4,5-bis(4-bromophenyl)-1-hexyl-1H-imidazol-2-yl]isoquinolin-3-ol as an antimicrobial compound | IRF3, IFNG, TLR4 | NAPRT 2198/4885TSHR 4653/4885TDP1 4349/4885 |
| US-12162839-B1 | 4,5-bis(4-bromophenyl)-2-(4-bromophenyl)-1-hexyl-1H-imidazole as an antimicrobial compound | BRD4, IL4, CASP4 | NAPRT 1702/4885TSHR 3702/4885TDP1 3863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.