Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 5/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14878202 | 0.84 | CHRNB4 (0.35) | CHRNB4CHRNA3CHRNB2CHRNA5CHRNA4 | |
| SCHEMBL19121074 | 0.80 | CCNE1 (0.35) | CHRNB4CHRNA3CHRNB2CHRNA5CHRNA4 | |
| SCHEMBL6959496 | 0.80 | CCNE1 (0.35) | CHRNB4CHRNA3CHRNB2CHRNA5CHRNA4 | |
| SCHEMBL6955594 | 0.80 | CCNE1 (0.35) | CHRNB4CHRNA3CHRNB2CHRNA5CHRNA4 | |
| SCHEMBL6979232 | 0.76 | CHRNB4 (0.41) | CHRNB4CHRNA3CHRNB2CHRNA5CHRNA4 | |
| SCHEMBL6976643 | 0.76 | CHRNB4 (0.41) | CHRNB4CHRNA3CHRNB2CHRNA5CHRNA4 | |
| SCHEMBL14380929 | 0.75 | — | — | |
| SCHEMBL6980143 | 0.72 | CHRNB4 (0.38) | CHRNB4CHRNA3CHRNB2CHRNA5CHRNA4 | |
| SCHEMBL6958880 | 0.71 | CHRNB4 (0.37) | CHRNB4CHRNA3CHRNB2CHRNA5CHRNA4 | |
| SCHEMBL6959571 | 0.69 | CHRNB4 (0.37) | CHRNB4CHRNA3CHRNB2CHRNA5CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374801-A1 | METHOD FOR PRODUCING QUINAZOLINE DERIVATIVE | Shionogi&Co., Ltd. (JP) | 2011-10-12 | — | — | EP | disclosed |