Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 7/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 7/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12202912 | 0.84 | CHRNB4 (0.35) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA5 | |
| SCHEMBL19121074 | 0.81 | CCNE1 (0.35) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA5 | |
| SCHEMBL6955594 | 0.81 | CCNE1 (0.35) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA5 | |
| SCHEMBL6959496 | 0.81 | CCNE1 (0.35) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA5 | |
| SCHEMBL14878203 | 0.81 | LTA4H (0.33) | — | |
| SCHEMBL6979232 | 0.80 | CHRNB4 (0.41) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA5 | |
| SCHEMBL6976643 | 0.80 | CHRNB4 (0.41) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA5 | |
| SCHEMBL14878201 | 0.78 | IRAK4 (0.31) | — | |
| SCHEMBL6980143 | 0.76 | CHRNB4 (0.38) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA5 | |
| SCHEMBL6958880 | 0.75 | CHRNB4 (0.37) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951051-B2 | Process for producing alkynylketone derivative | SHIONOGI & CO., LTD. (JP) | 2018-04-24 | — | — | US | disclosed |
| US-20170197943-A1 | PROCESS FOR PRODUCING ALKYNYLKETONE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2017-07-13 | — | — | US | disclosed |
| US-8426589-B2 | Process for production of quinazoline derivative | SHIONOGI & CO., LTD. (JP) | 2013-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170197943-A1 | PROCESS FOR PRODUCING ALKYNYLKETONE DERIVATIVE | PDK4, PDK3, PDK2 | CHRNB4 4768/4885CHRNA3 4762/4885CHRNB2 4780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.