Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | AGXT | P21549 | 2/20 | 0.43 |
| ▸ | FOXM1 | Q08050 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12204097 | 0.87 | OPRL1 (0.49) | OPRL1HTR2AHTR2CSLC6A4FOXM1 | |
| SCHEMBL12204106 | 0.85 | IDO1 (0.48) | OPRL1SLC6A4IDO1FOXM1KDM4E | |
| SCHEMBL29045802 | 0.84 | FOXM1 (0.61) | OPRL1HTR2AHTR2CSLC6A4FOXM1 | |
| SCHEMBL12204203 | 0.83 | FOXM1 (0.49) | OPRL1HTR2AHTR2CSLC6A4FOXM1 | |
| SCHEMBL24079779 | 0.78 | BCHE (0.59) | OPRL1KDM4ESMN1; SMN2BCHEACHE | |
| SCHEMBL22519849 | 0.75 | IDO1 (0.51) | HTR2AHTR2CSLC6A4IDO1AGXT | |
| SCHEMBL23074690 | 0.75 | ALDH1A1 (0.56) | OPRL1KDM4EALDH1A1 | |
| SCHEMBL18313743 | 0.74 | ALDH1A1 (0.50) | HTR2AHTR2CSLC6A4KDM4EALDH1A1 | |
| SCHEMBL29045820 | 0.74 | FOXM1 (0.61) | HTR2AHTR2CSLC6A4FOXM1KDM4E | |
| SCHEMBL19967537 | 0.73 | KDM4E (0.39) | HTR2AHTR2CSLC6A4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2377856-A1 | Urea glucokinase activators | NOVO NORDISK A/S (DK) | 2011-10-19 | — | — | EP | disclosed |