Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOXM1 | Q08050 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29045791 | 0.83 | FOXM1 (0.70) | FOXM1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL12204109 | 0.83 | OPRL1 (0.50) | FOXM1KDM4EALDH1A1OPRL1SMN1; SMN2 | |
| SCHEMBL12204774 | 0.83 | FOXM1 (0.49) | FOXM1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL12204763 | 0.82 | FOXM1 (0.46) | FOXM1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL12204207 | 0.79 | FOXM1 (0.68) | FOXM1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL24093122 | 0.77 | KMT2A (0.61) | KMT2AMEN1KDM4EALDH1A1GAA | |
| SCHEMBL12204305 | 0.77 | OPRL1 (0.42) | FOXM1KDM4EALDH1A1OPRL1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7018005 | 0.76 | FOXM1 (0.68) | FOXM1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL12204097 | 0.76 | OPRL1 (0.49) | FOXM1KDM4EALDH1A1OPRL1SMN1; SMN2 | |
| SCHEMBL12204080 | 0.74 | FOXM1 (0.42) | FOXM1KDM4EALDH1A1OPRL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2377856-A1 | Urea glucokinase activators | NOVO NORDISK A/S (DK) | 2011-10-19 | — | — | EP | disclosed |