Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26619760 | 0.80 | ITGB3 (0.45) | ITGB3ITGA2BSLC6A4SLC6A2HTR3A | |
| SCHEMBL12205066 | 0.78 | ITGB3 (0.46) | ITGB3ITGA2BSLC6A4SLC6A2HTR3A | |
| SCHEMBL12205163 | 0.78 | GPR119 (0.49) | ITGB3ITGA2BSLC6A4ITGAVCHRM2 | |
| SCHEMBL1575797 | 0.77 | GPR119 (0.63) | — | |
| SCHEMBL13144596 | 0.76 | ITGB3 (0.46) | ITGB3ITGA2BSLC6A4SLC6A2HTR3A | |
| SCHEMBL31574984 | 0.76 | ITGB3 (0.50) | ITGB3ITGA2BSLC6A4SLC6A2HTR3A | |
| SCHEMBL12205168 | 0.76 | ITGB3 (0.54) | ITGB3ITGA2BSLC6A4TDP1ITGAV | |
| SCHEMBL12103493 | 0.76 | ITGB3 (0.53) | ITGB3ITGA2BSLC6A4ITGAVCHRM2 | |
| SCHEMBL13534659 | 0.75 | ITGB3 (0.42) | ITGB3ITGA2BSLC6A4SLC6A2HTR3A | |
| Hydrochloric Acid SCHEMBL1296299 | 0.75 | ITGB3 (0.52) | ITGB3ITGA2BSLC6A4ITGAVCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2377863-A1 | Piperidine GPCR agonists | Prosidion Limited (GB) | 2011-10-19 | — | — | EP | disclosed |