Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | CBX7 | O95931 | 2/20 | 0.39 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.39 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.38 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.38 |
| ▸ | ELOVL6 | Q9H5J4 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | SNRNP200 | O75643 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11959125 | 0.85 | IDO1 (0.41) | IDO1CBX7CDYLCDYL2CDY1; CDY1B | |
| SCHEMBL2485622 | 0.75 | IDO1 (0.41) | IDO1CBX7CDYLCDYL2CDY1; CDY1B | |
| SCHEMBL16377143 | 0.74 | IDO1 (0.62) | IDO1CBX7CDYLCDYL2CDY1; CDY1B | |
| SCHEMBL2485481 | 0.73 | IDO1 (0.48) | IDO1CBX7CDYLCDYL2CDY1; CDY1B | |
| SCHEMBL11959113 | 0.70 | IDO1 (0.37) | IDO1SMN1; SMN2BCHEKMT2A | |
| SCHEMBL12205319 | 0.69 | PGR (0.43) | IDO1CBX7CDYLCDYL2CDY1; CDY1B | |
| SCHEMBL29276492 | 0.66 | IDO1 (0.54) | IDO1CBX7CDYLCDYL2CDY1; CDY1B | |
| SCHEMBL2482415 | 0.65 | PGR (0.41) | IDO1CBX7CDYLCDYL2CDY1; CDY1B | |
| SCHEMBL2480466 | 0.65 | IDO1 (0.42) | IDO1CBX7CDYLCDYL2CDY1; CDY1B | |
| SCHEMBL2484408 | 0.65 | IDO1 (0.43) | IDO1CBX7CDYLCDYL2CDY1; CDY1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891075-B1 | TRICYCLIC SPIRO DERIVATIVES AS CRTH2 MODULATORS | MERCK SERONO SA (CH) | 2011-10-19 | — | — | EP | disclosed |