Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | CASP1 | P29466 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | CASP7 | P55210 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL405253 | 0.80 | ALDH1A1 (0.70) | ALDH1A1MAPK1HSD17B10TSHRCASP1 | |
| SCHEMBL23081257 | 0.77 | ALDH1A1 (0.59) | ALDH1A1MAPK1HSD17B10TSHRCASP1 | |
| SCHEMBL15960556 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MAPK1HSD17B10TSHRCASP1 | |
| SCHEMBL8097609 | 0.76 | ALDH1A1 (0.64) | ALDH1A1MAPK1HSD17B10TSHRCASP1 | |
| SCHEMBL25009045 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MAPK1HSD17B10TSHRCASP1 | |
| SCHEMBL22824062 | 0.74 | ALDH1A1 (0.50) | ALDH1A1MAPK1HSD17B10TSHRCASP1 | |
| SCHEMBL23347093 | 0.74 | ALDH1A1 (0.50) | ALDH1A1MAPK1HSD17B10TSHRCASP1 | |
| SCHEMBL25009032 | 0.73 | MAPK1 (0.48) | ALDH1A1MAPK1HSD17B10TSHRCASP1 | |
| SCHEMBL23347102 | 0.73 | ALDH1A1 (0.48) | ALDH1A1MAPK1HSD17B10TSHRCASP1 | |
| SCHEMBL25009471 | 0.73 | ALDH1A1 (0.44) | ALDH1A1MAPK1HSD17B10TSHRCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8951648-B2 | Diacenaphtho[1,2-b:1′,2′-k]chrysene derivative | CANON KABUSHIKI KAISHA (JP) | 2015-02-10 | — | — | US | disclosed |
| US-8951648-B2 | Diacenaphtho[1,2-b:1′,2′-k]chrysene derivative | CANON KABUSHIKI KAISHA (JP) | 2015-02-10 | — | — | US | disclosed |
| US-20110251446-A1 | DIACENAPHTHO[1,2-b:1',2'-k]CHRYSENE DERIVATIVE | CANON KABUSHIKI KAISHA (JP) | 2011-10-13 | — | — | US | disclosed |
| US-20110251446-A1 | DIACENAPHTHO[1,2-b:1',2'-k]CHRYSENE DERIVATIVE | CANON KABUSHIKI KAISHA (JP) | 2011-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251446-A1 | DIACENAPHTHO[1,2-b:1',2'-k]CHRYSENE DERIVATIVE | DNAJB12, DNAJA1, DNAJA2 | ALDH1A1 1690/4885MAPK1 1190/4885HSD17B10 326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.