Sorbitol

Sorbitol

SCHEMBL1220679

C1CO1.C=CC.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
TDP1 Q9NUW8 1/20 0.48
KDM4E B2RXH2 2/20 0.41
PDE4A P27815 1/20 0.37
USP2 O75604 1/20 0.34
SLCO1B1 Q9Y6L6 1/20 0.34
TOP1 P11387 1/20 0.34
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mannitol SCHEMBL28092438 0.88 LMNA (0.65) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL27743384 0.85 LMNA (0.61) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL25292996 0.85 LMNA (0.69) LMNAL3MBTL1TDP1KDM4EPDE4A
Sorbitol SCHEMBL1091804 0.85 LMNA (0.69) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL27695681 0.83 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
Sorbitol SCHEMBL2418929 0.83 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL22575783 0.83 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
Xylitol SCHEMBL9070177 0.83 LMNA (0.56) LMNAL3MBTL1TDP1KDM4EPDE4A
Glycerin SCHEMBL1220974 0.81 LMNA (0.45) LMNATDP1USP2MAPT
Mannitol SCHEMBL20640359 0.81 LMNA (0.55) LMNAL3MBTL1TDP1KDM4EPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110039959-A1 POLYOL INCLUDED PHOSPHORUS AND NITROGEN KIM DO-GYUN 2011-02-17 US disclosed
WO-2009002100-A2 POLYOL INCLUDED PHOSPHORUS AND NITROGEN KIM DO-GYUN (KR) 2008-12-31 WO disclosed