Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
| ▸ | TOP1 | P11387 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mannitol SCHEMBL28092438 | 0.94 | LMNA (0.65) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Mannitol SCHEMBL27743384 | 0.92 | LMNA (0.61) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Sorbitol SCHEMBL2418929 | 0.89 | LMNA (0.58) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Mannitol SCHEMBL22575783 | 0.89 | LMNA (0.58) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Mannitol SCHEMBL20640359 | 0.87 | LMNA (0.55) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Adonitol SCHEMBL28860963 | 0.83 | LMNA (0.43) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Sorbitol SCHEMBL1220679 | 0.83 | LMNA (0.50) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| E968 SCHEMBL14793512 | 0.82 | LMNA (0.40) | LMNAL3MBTL1TDP1KDM4ETSHR | |
| Xylitol SCHEMBL6240620 | 0.81 | LMNA (0.71) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Adonitol SCHEMBL28031758 | 0.81 | LMNA (0.71) | LMNAL3MBTL1TDP1KDM4EPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516544-A | DIETETICS WITH LOW CALORIE FAT SUBSTITUTES USING ESTERIFIED POLYOXYPROPYLENE GLYCOL-GLYCEROL DERIVATIVES | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1996-05-14 | — | — | US | disclosed |
| US-5427815-A | Polyesterether copolymer | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1995-06-27 | — | — | US | disclosed |