⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22615908 | 0.75 | — | — | |
| SCHEMBL12207163 | 0.75 | GABRP (0.34) | — | |
| SCHEMBL2711026 | 0.74 | — | — | |
| SCHEMBL22615907 | 0.72 | ALDH1A1 (0.31) | — | |
| SCHEMBL14994538 | 0.69 | — | — | |
| SCHEMBL22615893 | 0.69 | CA1 (0.32) | — | |
| SCHEMBL14993694 | 0.67 | — | — | |
| SCHEMBL12207168 | 0.66 | GABRP (0.32) | — | |
| SCHEMBL60538 | 0.65 | — | — | |
| SCHEMBL14021451 | 0.63 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2785703-B1 | 5-Fluorinated derivatives of Meldrum's acid (5-fluoro-1,3-dioxane-4,6-dione derivatives), methods for their preparation and their use as solvent additives in lithium ion batteries. | SOLVAY (BE) | 2017-01-11 | — | — | EP | claimed |
| US-20140322618-A1 | FLUORINATED DERIVATIVES OF MELDRUM'S ACID, A METHOD FOR THE PREPARATION OF THE SAME, AND THEIR USE AS A SOLVENT ADDITIVE | SOLVAY SA (BE) | 2014-10-30 | — | — | US | claimed |
| EP-2785703-A1 | FLUORINATED DERIVATIVES OF MELDRUM'S ACID, A METHOD FOR THE PREPARATION OF THE SAME, AND THEIR USE AS A SOLVENT ADDITIVE | Solvay SA (BE) | 2014-10-08 | — | — | EP | claimed |
| WO-2013079397-A1 | FLUORINATED DERIVATIVES OF MELDRUM'S ACID, A METHOD FOR THE PREPARATION OF THE SAME, AND THEIR USE AS A SOLVENT ADDITIVE | SOLVAY SA (BE) | 2013-06-06 | — | — | WO | claimed |
| US-9825331-B2 | Fluorinated derivatives of meldrum's acid, a method for the preparation of the same, and their use as a solvent additive | SOLVAY SA (BE) | 2017-11-21 | — | — | US | disclosed |
| US-9825331-B2 | Fluorinated derivatives of meldrum's acid, a method for the preparation of the same, and their use as a solvent additive | SOLVAY SA (BE) | 2017-11-21 | — | — | US | disclosed |
| US-9825331-B2 | Fluorinated derivatives of meldrum's acid, a method for the preparation of the same, and their use as a solvent additive | SOLVAY SA (BE) | 2017-11-21 | — | — | US | disclosed |
| EP-2785703-B1 | 5-Fluorinated derivatives of Meldrum's acid (5-fluoro-1,3-dioxane-4,6-dione derivatives), methods for their preparation and their use as solvent additives in lithium ion batteries. | SOLVAY (BE) | 2017-01-11 | — | — | EP | disclosed |
| US-20140322618-A1 | FLUORINATED DERIVATIVES OF MELDRUM'S ACID, A METHOD FOR THE PREPARATION OF THE SAME, AND THEIR USE AS A SOLVENT ADDITIVE | SOLVAY SA (BE) | 2014-10-30 | — | — | US | disclosed |
| US-20140322618-A1 | FLUORINATED DERIVATIVES OF MELDRUM'S ACID, A METHOD FOR THE PREPARATION OF THE SAME, AND THEIR USE AS A SOLVENT ADDITIVE | SOLVAY SA (BE) | 2014-10-30 | — | — | US | disclosed |
| US-20140322618-A1 | FLUORINATED DERIVATIVES OF MELDRUM'S ACID, A METHOD FOR THE PREPARATION OF THE SAME, AND THEIR USE AS A SOLVENT ADDITIVE | SOLVAY SA (BE) | 2014-10-30 | — | — | US | disclosed |
| EP-2785703-A1 | FLUORINATED DERIVATIVES OF MELDRUM'S ACID, A METHOD FOR THE PREPARATION OF THE SAME, AND THEIR USE AS A SOLVENT ADDITIVE | Solvay SA (BE) | 2014-10-08 | — | — | EP | disclosed |
| WO-2013079397-A1 | FLUORINATED DERIVATIVES OF MELDRUM'S ACID, A METHOD FOR THE PREPARATION OF THE SAME, AND THEIR USE AS A SOLVENT ADDITIVE | SOLVAY SA (BE) | 2013-06-06 | — | — | WO | disclosed |
| EP-2380882-A1 | Salts of heterocyclic anions and their uses as ionic conductive materials | HYDRO QUEBEC (CA) | 2011-10-26 | — | — | EP | disclosed |
| EP-0850932-B1 | Salts of heterocyclic anions and their uses as ionic conductive materials | CENTRE NAT RECH SCIENT (FR) | 2009-07-22 | — | — | EP | disclosed |