SCHEMBL1220922

SCHEMBL1220922

N#Cc1nc(Br)[nH]c1C#N

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
MAPK1 P28482 1/20 0.46
USP8 P40818 1/20 0.30
USP7 Q93009 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3108326 0.78
SCHEMBL18320214 0.73 ALDH1A1 (0.47) ALDH1A1MAPK1
SCHEMBL1529256 0.71 ALDH1A1 (0.46) ALDH1A1MAPK1
SCHEMBL22292201 0.71 ALDH1A1 (0.46) ALDH1A1MAPK1
SCHEMBL6267870 0.71 ALDH1A1 (0.50) ALDH1A1MAPK1
SCHEMBL11662504 0.71 ALDH1A1 (0.46) ALDH1A1MAPK1
SCHEMBL404890 0.71 ALDH1A1 (0.46) ALDH1A1MAPK1USP8
SCHEMBL13217085 0.71 ALDH1A1 (0.46) ALDH1A1MAPK1
SCHEMBL11662467 0.71 ALDH1A1 (0.46) ALDH1A1MAPK1
SCHEMBL8493480 0.71 ALDH1A1 (0.42) ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119613465-A Chemical synthesis method of haemophilus influenzae type b capsular polysaccharide derivative 江南大学 2025-03-14 CN claimed
WO-2025038661-A1 OLIGONUCLEOTIDE SYNTHESIS METHODS Arrowhead Pharmaceuticals, Inc. (US) 2025-02-20 WO claimed
CN-114835908-A Preparation of metal-organic framework material for separating ethane/ethylene and application thereof 南开大学 2022-08-02 CN claimed
EP-0904275-B1 PREPARATION OF PHOSPHOROTHIOATE OLIGOMERS UNIV MCGILL (CA) 2006-05-17 EP claimed
EP-4720050-A1 PROCESS OF PREPARING HIV CAPSID INHIBITOR GILEAD SCIENCES, INC. (US) 2026-04-08 EP disclosed
EP-4695265-A1 METHOD AND COMPOSITION FOR OLIGONUCLEOTIDE SYNTHESIS Bachem Holding AG (CH) 2026-02-18 EP disclosed
US-20260001902-A1 IMPROVED OLIGONUCLEOTIDE SYNTHESIS BACHEM HOLDING AG (CH) 2026-01-01 US disclosed
EP-4605403-B1 METHOD AND COMPOSITION FOR OLIGONUCLEOTIDE SYNTHESIS BACHEM HOLDING AG (CH) 2025-11-26 EP disclosed
EP-4605403-A1 METHOD AND COMPOSITION FOR OLIGONUCLEOTIDE SYNTHESIS Bachem Holding AG (CH) 2025-08-27 EP disclosed
EP-4590684-A1 IMPROVED OLIGONUCLEOTIDE SYNTHESIS Bachem Holding AG (CH) 2025-07-30 EP disclosed
WO-2025082632-A1 METHOD AND COMPOSITION FOR OLIGONUCLEOTIDE SYNTHESIS BACHEM HOLDING AG (CH) 2025-04-24 WO disclosed
CN-119613465-A Chemical synthesis method of haemophilus influenzae type b capsular polysaccharide derivative 江南大学 2025-03-14 CN disclosed
US-5480884-A Compounds having a guanidine structure CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1996-01-02 US disclosed
EP-0412849-B1 Azole pesticides AGREVO UK LTD (GB) 1995-12-20 EP disclosed
CN-1025582-C Azole pesticides SCHERING AGROCHEMICALS LTD (GB) 1994-08-10 CN disclosed
WO-1993010102-A1 NOVEL COMPOUNDS HAVING A GUANIDINE STRUCTURE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) 1993-05-27 WO disclosed
US-5189053-A Insecticide, acaricide and endoparasiticide SCHERING AGROCHEMICALS LIMITED (GB) 1993-02-23 US disclosed
US-5109012-A 2-IMIDAZOL(IN)E SUBSTITUTED ARYL-1,2,3-TRIAZOLE PESTICIDES SCHERING AGROCHEMICALS LIMITED (GB) 1992-04-28 US disclosed
CN-1049341-A AZOLE PESTICIDES SCHERING AGROCHEMICALS LTD (GB) 1991-02-20 CN disclosed
EP-0412849-A2 Azole pesticides AgrEvo UK Limited (GB) 1991-02-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001902-A1 IMPROVED OLIGONUCLEOTIDE SYNTHESIS MED1, POLRMT, CPSF6 ALDH1A1 1937/4885MAPK1 970/4885USP8 4020/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.