Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2197826 | 0.93 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAL3MBTL1CYP19A1CYP17A1 | |
| SCHEMBL12211586 | 0.91 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAL3MBTL1CYP19A1CYP17A1 | |
| SCHEMBL2199854 | 0.84 | CYP19A1 (0.44) | SMN1; SMN2LMNAL3MBTL1CYP19A1CYP17A1 | |
| SCHEMBL2195573 | 0.82 | BRD4 (0.42) | SMN1; SMN2LMNAL3MBTL1CYP19A1CYP17A1 | |
| SCHEMBL2197190 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAL3MBTL1CYP19A1CYP17A1 | |
| SCHEMBL2197035 | 0.80 | ATM (0.45) | SMN1; SMN2LMNAL3MBTL1CYP19A1CYP17A1 | |
| SCHEMBL2198631 | 0.80 | ATM (0.45) | SMN1; SMN2LMNAL3MBTL1CYP19A1CYP17A1 | |
| SCHEMBL12211600 | 0.79 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNAL3MBTL1CYP19A1CYP17A1 | |
| SCHEMBL2196294 | 0.79 | L3MBTL1 (0.44) | SMN1; SMN2LMNAL3MBTL1CYP19A1CYP17A1 | |
| SCHEMBL2198129 | 0.79 | KCNA5 (0.47) | SMN1; SMN2LMNAL3MBTL1CYP19A1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110251066-A1 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | SYNGENTA CROP PROTECTION LLC (US) | 2011-10-13 | — | — | US | disclosed |
| US-20110251066-A1 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | SYNGENTA CROP PROTECTION LLC (US) | 2011-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251066-A1 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | CYP4Z1, CYP4X1, AGXT | SMN1; SMN2 4879/4885LMNA 4574/4885L3MBTL1 4082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.