Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.43 |
| ▸ | CETP | P11597 | 6/20 | 0.41 |
| ▸ | AKT2 | P31751 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7842574 | 0.99 | TACR1 (0.53) | TACR1LMNASLC6A2CETPAKT2 | |
| SCHEMBL12586089 | 0.82 | TACR1 (0.56) | TACR1SLC6A2CETPAKT2DAO | |
| Hydrochloric Acid SCHEMBL7840218 | 0.76 | TACR1 (0.48) | TACR1LMNASLC6A2CETPAKT2 | |
| SCHEMBL7831549 | 0.76 | LMNA (0.50) | TACR1LMNA | |
| Hydrochloric Acid SCHEMBL7831856 | 0.74 | GAA (0.48) | LMNASLC6A2 | |
| SCHEMBL1220833 | 0.74 | GAA (0.48) | LMNA | |
| Hydrochloric Acid SCHEMBL28686967 | 0.73 | GAA (0.47) | LMNA | |
| SCHEMBL8162240 | 0.72 | TACR1 (0.45) | TACR1LMNASLC6A2FFAR4CHRM3 | |
| SCHEMBL92907 | 0.72 | CETP (0.55) | CETPDAOCHRM3 | |
| SCHEMBL2274564 | 0.71 | TACR1 (0.53) | TACR1SLC6A2PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110046179-A1 | NOVEL PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2011-02-24 | — | — | US | claimed |
| US-20110046179-A1 | NOVEL PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2011-02-24 | — | — | US | disclosed |
| EP-2059506-A1 | NOVEL PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2009-05-20 | — | — | EP | disclosed |
| WO-2008025777-A1 | NOVEL PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2008-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046179-A1 | NOVEL PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | SLC18A2, SLC18A3, SLC6A2 | TACR1 48/4885LMNA 4358/4885SLC6A2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.