Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7840218 | 0.84 | TACR1 (0.48) | TACR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7841113 | 0.78 | TYRO3 (0.37) | ALDH1A1DRD2DRD4 | |
| SCHEMBL7838476 | 0.76 | MEN1 (0.54) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL8162238 | 0.75 | TACR1 (0.46) | TACR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1222020 | 0.72 | TACR1 (0.54) | TACR1FFAR4LMNACHRM3SLC6A2 | |
| SCHEMBL12586089 | 0.72 | TACR1 (0.56) | TACR1FFAR4CHRM3SLC6A2CHRM2 | |
| Hydrochloric Acid SCHEMBL7842574 | 0.72 | TACR1 (0.53) | TACR1FFAR4LMNACHRM3SLC6A2 | |
| SCHEMBL7831549 | 0.71 | LMNA (0.50) | TACR1MEN1KMT2AALDH1A1AMPD2 | |
| SCHEMBL27772416 | 0.69 | VNN1 (0.50) | AMPD2CHRM3CHRM2CHRM1MAPK14 | |
| SCHEMBL7840409 | 0.68 | SSTR4 (0.42) | MEN1KMT2AALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000016778-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 2000-03-30 | — | — | WO | disclosed |