Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.62 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.62 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.62 |
| ▸ | CES2 | O00748 | 2/20 | 0.58 |
| ▸ | CES1 | P23141 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | DAO | P14920 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21755166 | 1.00 | PARP1 (1.00) | PARP1TSHRPOLBCYP3A4MAPT | |
| Benzamide SCHEMBL30112947 | 1.00 | PARP1 (1.00) | PARP1TSHRPOLBCYP3A4MAPT | |
| Benzamide SCHEMBL11668921 | 1.00 | PARP1 (1.00) | PARP1TSHRPOLBCYP3A4MAPT | |
| Benzamide SCHEMBL6690447 | 1.00 | PARP1 (1.00) | PARP1TSHRPOLBCYP3A4MAPT | |
| Benzamide SCHEMBL16352 | 1.00 | — | — | |
| Benzamide SCHEMBL27963599 | 1.00 | PARP1 (1.00) | PARP1TSHRPOLBCYP3A4MAPT | |
| Benzamide SCHEMBL29618402 | 1.00 | — | — | |
| Benzamide SCHEMBL1332331 | 1.00 | — | — | |
| Benzamide SCHEMBL8961640 | 0.97 | PARP1 (0.94) | PARP1TSHRPOLBCYP3A4MAPT | |
| Benzamide SCHEMBL3864950 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227272-A1 | BIFUNCTIONAL do2pa DERIVATIVES, CHELATES WITH METALLIC CATIONS AND USE THEREOF | Centre National de la Recherche Scientifique (CNRS) (FR) | 2017-10-11 | — | — | EP | disclosed |
| CN-103819459-B | Anti-Viral Compounds | 艾伯维巴哈马有限公司 | 2017-05-17 | — | — | CN | disclosed |
| CN-106573929-A | 1h-1,8- naphthyridin-2ones as anti proliferative compounds | 纳科法尔马有限公司 | 2017-04-19 | — | — | CN | disclosed |
| WO-2016087667-A1 | BIFUNCTIONAL do2pa DERIVATIVES, CHELATES WITH METALLIC CATIONS AND USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2016-06-09 | — | — | WO | disclosed |
| CN-103172620-B | Anti-viral compounds | Abbott Labaoratories (BS) | 2014-10-29 | — | — | CN | disclosed |
| CN-103819459-A | Anti-Viral Compounds | Abbott Labaoratories | 2014-05-28 | — | — | CN | disclosed |
| CN-103819537-A | Anti-viral compounds | Abbott Labaoratories | 2014-05-28 | — | — | CN | disclosed |
| CN-102333772-B | Antiviral compounds | ABBOTT LAB | 2013-12-11 | — | — | CN | disclosed |
| CN-103172620-A | Anti-viral compounds | Abbott Labaoratories | 2013-06-26 | — | — | CN | disclosed |
| CN-102333772-A | Antiviral compounds | ABBOTT LAB | 2012-01-25 | — | — | CN | disclosed |
| CN-1104439-C | Phenyl-substituted 4-azasteroid fluoro derivatives, process for their preparation and their use as medicaments | PHAMACIA & UPJOHN S P A (IT) | 2003-04-02 | — | — | CN | disclosed |
| CN-1313762-A | Apomorphine-containing dosage forms for ameliorating male erectile dysfunction | PENTECH PHARMACEUTICALS INC (US) | 2001-09-19 | — | — | CN | disclosed |
| CN-1218399-A | Benzamide treatment of dementia associated with AIDs virus (HIV-4) infection | CENTAUR PHARMACEUTICALS INC (US) | 1999-06-02 | — | — | CN | disclosed |
| CN-1165520-A | Phenylsubstituted 4-azasteroid fluoroderivatives | PHARMACIA SPA (IT) | 1997-11-19 | — | — | CN | disclosed |
| US-5382600-A | 3,3-diphenylpropylamines and pharmaceutical compositions thereof | PHARMACIA AKTIEBOLAG (SE) | 1995-01-17 | — | — | US | disclosed |
| US-5167876-A | Protective clothing; military aircraft interiors | ALLIED-SIGNAL INC. (US) | 1992-12-01 | — | — | US | disclosed |
| EP-0325571-B1 | NEW AMINES, THEIR USE AND PREPARATION | Kabi Pharmacia AB (SE) | 1991-08-07 | — | — | EP | disclosed |
| EP-0354234-A1 | NEW AMINES, THEIR USE AND PREPARATION | KabiVitrum AB (SE) | 1990-02-14 | — | — | EP | disclosed |
| WO-1989006644-A1 | NEW AMINES, THEIR USE AND PREPARATION | KABIVITRUM AB (SE) | 1989-07-27 | — | — | WO | disclosed |
| EP-0325571-A1 | New amines, their use and preparation | Kabi Pharmacia AB (SE) | 1989-07-26 | — | — | EP | disclosed |