Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.62 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.62 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.62 |
| ▸ | CES2 | O00748 | 2/20 | 0.58 |
| ▸ | CES1 | P23141 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | DAO | P14920 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21755166 | 1.00 | PARP1 (1.00) | PARP1TSHRPOLBCYP3A4MAPT | |
| Benzamide SCHEMBL30112947 | 1.00 | PARP1 (1.00) | PARP1TSHRPOLBCYP3A4MAPT | |
| Benzamide SCHEMBL11668921 | 1.00 | PARP1 (1.00) | PARP1TSHRPOLBCYP3A4MAPT | |
| Benzamide SCHEMBL1222101 | 1.00 | PARP1 (1.00) | PARP1TSHRPOLBCYP3A4MAPT | |
| Benzamide SCHEMBL16352 | 1.00 | — | — | |
| Benzamide SCHEMBL27963599 | 1.00 | PARP1 (1.00) | PARP1TSHRPOLBCYP3A4MAPT | |
| Benzamide SCHEMBL29618402 | 1.00 | — | — | |
| Benzamide SCHEMBL1332331 | 1.00 | — | — | |
| Benzamide SCHEMBL8961640 | 0.97 | PARP1 (0.94) | PARP1TSHRPOLBCYP3A4MAPT | |
| Benzamide SCHEMBL3864950 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10632209-B2 | ASH1L inhibitors and methods of treatment therewith | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2020-04-28 | — | — | US | claimed |
| CN-103651352-B | New application of N-(2-phenoxy benzene) benzamide compound as agricultural bactericide | UNIV SICHUAN | 2015-05-13 | — | — | CN | claimed |
| CN-103651352-A | New application of N-(2-phenoxy benzene) benzamide compound as agricultural bactericide | UNIV SICHUAN | 2014-03-26 | — | — | CN | claimed |
| US-11833210-B2 | ASH1L inhibitors and methods of treatment therewith | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2023-12-05 | — | — | US | disclosed |
| US-11147885-B2 | ASH1L inhibitors and methods of treatment therewith | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2021-10-19 | — | — | US | disclosed |
| EP-3706737-A1 | ASH1L INHIBITORS AND METHODS OF TREATMENT THEREWITH | The Regents of the University of Michigan (US) | 2020-09-16 | — | — | EP | disclosed |
| US-20200246474-A1 | ASH1L INHIBITORS AND METHODS OF TREATMENT THEREWITH | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2020-08-06 | — | — | US | disclosed |
| US-10632209-B2 | ASH1L inhibitors and methods of treatment therewith | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2020-04-28 | — | — | US | disclosed |
| US-20190144442-A1 | ASH1L INHIBITORS AND METHODS OF TREATMENT THEREWITH | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2019-05-16 | — | — | US | disclosed |
| CN-109715628-A | Novel Mesoionic Insecticidal Compounds | 日本化药株式会社 | 2019-05-03 | — | — | CN | disclosed |
| CN-108586279-A | One inter-species diamide compound and its preparation method and application | 上海泰禾国际贸易有限公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-102597026-A | Process and catalyst system for polydiene production | BRIDGESTONE CORP | 2012-07-18 | — | — | CN | disclosed |
| CN-102482375-A | PROCESS FOR PRODUCING POLYDIENES | BRIDGESTONE CORP | 2012-05-30 | — | — | CN | disclosed |
| CN-101874044-A | Polymers functionalized with heterocyclic nitrile compounds | BRIDGESTONE CORP | 2010-10-27 | — | — | CN | disclosed |
| CN-101475655-A | Process for producing polydienes | BRIDGESTONE CORP (JP) | 2009-07-08 | — | — | CN | disclosed |
| CN-101362808-A | Polyhydroxy compounds as polymerization quenchers | BRIDGESTONE CO LTD (JP) | 2009-02-11 | — | — | CN | disclosed |
| EP-0950669-B1 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM & HAAS (US) | 2004-09-08 | — | — | EP | disclosed |
| US-6306991-B1 | TWO PART COATING COMPOSITION WITH TWO CONTAINERS, OXIDATIVE POLYMERS WITH CROSSLINKABLE FUNCTIONAL GROUPS | ROHM AND HAAS COMPANY | 2001-10-23 | — | — | US | disclosed |
| US-6149977-A | CONTACTING THE OXIDATIVE POLYMER WITH A CATALYTIC AMOUNT OF AN OXIDIZING ENZYME, SUCH AS HORSERADISH PEROXIDASE. | ROHM AND HAAS COMPANY (US) | 2000-11-21 | — | — | US | disclosed |
| EP-0950669-A2 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM AND HAAS COMPANY (US) | 1999-10-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11833210-B2 | ASH1L inhibitors and methods of treatment therewith | ASH1L, DOT1L, ASH2L | PARP1 1906/4885TSHR 4502/4885POLB 2738/4885 |
| US-20190144442-A1 | ASH1L INHIBITORS AND METHODS OF TREATMENT THEREWITH | ASH1L, DOT1L, ASH2L | PARP1 1906/4885TSHR 4502/4885POLB 2738/4885 |
| US-10632209-B2 | ASH1L inhibitors and methods of treatment therewith | ASH1L, DOT1L, ASH2L | PARP1 1906/4885TSHR 4502/4885POLB 2738/4885 |
| US-20200246474-A1 | ASH1L INHIBITORS AND METHODS OF TREATMENT THEREWITH | ASH1L, DOT1L, ASH2L | PARP1 1906/4885TSHR 4502/4885POLB 2738/4885 |
| US-11147885-B2 | ASH1L inhibitors and methods of treatment therewith | ASH1L, DOT1L, ASH2L | PARP1 1906/4885TSHR 4502/4885POLB 2738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.