SCHEMBL12221124

SCHEMBL12221124

CC1=NN(c2ccccc2)C(=O)C1=C1Sc2c(O)c3c(c(O)c2S1)SC(=C1C(=O)N(c2ccccc2)N=C1C)S3

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 12/20 0.55
▸ KMT2A Q03164 11/20 0.55
▸ ALDH1A1 P00352 9/20 0.55
▸ MEN1 O00255 8/20 0.55
▸ GAA P10253 5/20 0.55
▸ KDM4E B2RXH2 6/20 0.45
▸ TDP1 Q9NUW8 6/20 0.44
▸ L3MBTL1 Q9Y468 5/20 0.44
▸ HPGD P15428 3/20 0.44
▸ PKM P14618 2/20 0.44
▸ HSP90AA1 P07900 1/20 0.44
▸ MAPK1 P28482 6/20 0.42
▸ HTT P42858 3/20 0.42
▸ LMNA P02545 2/20 0.42
▸ POLB P06746 2/20 0.42
▸ SMN1; SMN2 Q16637 3/20 0.41
▸ CYP1A2 P05177 1/20 0.41
▸ CHRM2 P08172 1/20 0.41
▸ CYP3A4 P08684 1/20 0.41
▸ CHRM1 P11229 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12243004 0.89 MAPT (0.44) MAPTKMT2AALDH1A1MEN1GAA
SCHEMBL12221247 0.89 MAPT (0.44) MAPTKMT2AALDH1A1MEN1GAA
SCHEMBL12221126 0.84 KMT2A (0.49) MAPTKMT2AALDH1A1MEN1GAA
SCHEMBL12221149 0.83 MAPT (0.54) MAPTKMT2AALDH1A1MEN1GAA
SCHEMBL12221125 0.82 KMT2A (0.51) MAPTKMT2AALDH1A1MEN1GAA
SCHEMBL12221128 0.81 KMT2A (0.46) MAPTKMT2AALDH1A1MEN1GAA
SCHEMBL12221153 0.80 KMT2A (0.39) MAPTKMT2AALDH1A1MEN1GAA
SCHEMBL12291974 0.80 MAPT (0.64) MAPTKMT2AALDH1A1MEN1GAA
SCHEMBL12242349 0.80 KMT2A (0.45) MAPTKMT2AALDH1A1MEN1GAA
SCHEMBL12221131 0.80 KMT2A (0.51) MAPTKMT2AALDH1A1MEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11364710-B2 Composition, film, glass article, compound, high purity composition, method for producing compound, and method for producing film FUJIFILM CORPORATION (JP) 2022-06-21 — — US disclosed
US-8039532-B2 Heterocyclic compound, ultraviolet absorbent and composition containing the same FUJIFILM CORPORATION (JP) 2011-10-18 — — US disclosed
US-8039532-B2 Heterocyclic compound, ultraviolet absorbent and composition containing the same FUJIFILM CORPORATION (JP) 2011-10-18 — — US disclosed
US-20100210762-A1 HETEROCYCLIC COMPOUND, ULTRAVIOLET ABSORBENT AND COMPOSITION CONTAINING THE SAME FUJIFILM CORPORATION (JP) 2010-08-19 — — US disclosed
US-20100210762-A1 HETEROCYCLIC COMPOUND, ULTRAVIOLET ABSORBENT AND COMPOSITION CONTAINING THE SAME FUJIFILM CORPORATION (JP) 2010-08-19 — — US disclosed
US-20090240067-A1 METHOD OF PRODUCING A BISBENZODITHIOL COMPOUND FUJIFILM CORPORATION (JP) 2009-09-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100210762-A1 HETEROCYCLIC COMPOUND, ULTRAVIOLET ABSORBENT AND COMPOSITION CONTAINING THE SAME F12, F2, CYP24A1 MAPT 4121/4885KMT2A 4498/4885ALDH1A1 1492/4885
US-20090240067-A1 METHOD OF PRODUCING A BISBENZODITHIOL COMPOUND SQOR, NQO1, PBRM1 MAPT 3419/4885KMT2A 1603/4885ALDH1A1 739/4885
US-11364710-B2 Composition, film, glass article, compound, high purity composition, method for producing compound, and method for producing film SOST, VCL, CCNO MAPT 30/4885KMT2A 892/4885ALDH1A1 3577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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