Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.42 |
| ▸ | ABAT | P80404 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14652352 | 0.82 | ALDH1A1 (0.39) | ESR1ALDH1A1MAPTESR2BLM | |
| SCHEMBL12899444 | 0.79 | NPC1 (0.42) | ESR1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL17694420 | 0.79 | HCAR2 (0.50) | ESR1KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL12309927 | 0.79 | ESR1 (0.61) | ABATESR1LMNAHPGDESR2 | |
| SCHEMBL15443987 | 0.77 | ESR1 (0.43) | ESR1CYP2A6ALDH1A1MAPTHPGD | |
| SCHEMBL13809203 | 0.77 | ESR1 (0.43) | EPHX2ESR1ALDH1A1ESR2BLM | |
| SCHEMBL15457714 | 0.77 | ESR1 (0.43) | EPHX2ESR1ESR2BLM | |
| SCHEMBL13078449 | 0.77 | ESR1 (0.43) | ESR1KDM4ECYP2A6ALDH1A1MAPT | |
| SCHEMBL2646831 | 0.77 | ESR1 (0.52) | ALDH5A1ABATEPHX2NR1H4ESR1 | |
| SCHEMBL15443986 | 0.76 | ESR1 (0.42) | ESR1ESR2BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016029324-A1 | AZASULFURYLPEPTIDE-BASED CD36 MODULATORS AND USES THEREOF | RSEM, LIMITED PARTNERSHIP (CA) | 2016-03-03 | — | — | WO | disclosed |
| US-9075058-B2 | Coelenterazine analogues and coelenteramide analogues | JNC CORPORATION (JP) | 2015-07-07 | — | — | US | disclosed |
| US-9056840-B2 | Coelenterazine analogues and coelenteramide analogues | JNC CORPORATION (JP) | 2015-06-16 | — | — | US | disclosed |
| US-20150153344-A1 | COELENTERAZINE ANALOGUES AND COELENTERAMIDE ANALOGUES | JNC CORP (JP) | 2015-06-04 | — | — | US | disclosed |
| US-8883432-B2 | Coelenterazine analogues and coelenteramide analogues | JNC CORPORATION (JP) | 2014-11-11 | — | — | US | disclosed |
| US-20140316137-A1 | COELENTERAZINE ANALOGUES AND COELENTERAMIDE ANALOGUES | JNC CORP (JP) | 2014-10-23 | — | — | US | disclosed |
| EP-2462138-B1 | ANTIVIRAL COMPOUNDS AND METHODS OF MAKING | VERSITECH LTD (CN) | 2014-09-24 | — | — | EP | disclosed |
| US-20140120538-A1 | COELENTERAZINE ANALOGUES AND COELENTERAMIDE ANALOGUES | NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY (JP) | 2014-05-01 | — | — | US | disclosed |
| US-8642281-B2 | Coelenterazine analogues and coelenteramide analogues | JNC CORPORATION (JP) | 2014-02-04 | — | — | US | disclosed |
| US-20110244481-A1 | COELENTERAZINE ANALOGUES AND COELENTERAMIDE ANALOGUES | JNC CORPORATION (JP) | 2011-10-06 | — | — | US | disclosed |
| WO-2011015037-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THERE OF CROSS REFERENCE TO RELATED APPLICATIONS | THE UNIVERSITY OF HONGKONG (CN) | 2011-02-10 | — | — | WO | disclosed |
| WO-2009105214-A2 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | RADIUS HEALTH, INC. (US) | 2009-08-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140120538-A1 | COELENTERAZINE ANALOGUES AND COELENTERAMIDE ANALOGUES | CCKAR, SI, GLP1R | ALDH5A1 2967/4885ABAT 2689/4885EPHX2 2136/4885 |
| US-20140316137-A1 | COELENTERAZINE ANALOGUES AND COELENTERAMIDE ANALOGUES | CCKAR, SI, GLP1R | ALDH5A1 2745/4885ABAT 2691/4885EPHX2 2387/4885 |
| US-20110244481-A1 | COELENTERAZINE ANALOGUES AND COELENTERAMIDE ANALOGUES | CCKAR, SI, GLP1R | ALDH5A1 2967/4885ABAT 2689/4885EPHX2 2136/4885 |
| US-20150153344-A1 | COELENTERAZINE ANALOGUES AND COELENTERAMIDE ANALOGUES | CCKAR, SI, GLP1R | ALDH5A1 2967/4885ABAT 2689/4885EPHX2 2136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.