SCHEMBL1222657

SCHEMBL1222657

FC(F)(Cl)C(F)(Cl)C(F)(F)Cl

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
CYP2E1 P05181 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL710882 0.89 ALDH1A1 (0.30) ALDH1A1LMNACYP2E1TSHR
SCHEMBL8677456 0.80
SCHEMBL865476 0.80
SCHEMBL108730 0.80
SCHEMBL1899391 0.77
SCHEMBL8850226 0.77
SCHEMBL1898495 0.77
SCHEMBL8680161 0.77
Dichlorotetrafluoroethane SCHEMBL865 0.76
SCHEMBL708774 0.74 LMNA (0.30) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119776053-A Insulating oil and preparation method thereof 清华大学 2025-04-08 CN claimed
CN-119662220-A Cooling liquid and preparation method thereof 清华大学 2025-03-21 CN claimed
CN-118064114-A Battery immersed type cooling liquid and preparation method and application thereof 清华大学 2024-05-24 CN claimed
CN-117942524-A Battery fire extinguishing agent and preparation method and application thereof 清华大学 2024-04-30 CN claimed
CN-117721451-A Organic blackening oil and preparation method thereof 江苏甬怡紧固件有限公司 2024-03-19 CN claimed
CN-114672362-A Modified mineral oil and preparation method thereof 清华大学 2022-06-28 CN claimed
EP-0728126-B1 PREPARATION OF 1,1,2,3,3-PENTAFLUOROPROPANE ALLIED SIGNAL INC (US) 1999-05-26 EP claimed
US-5880317-A Preparation of 1,1,2,3,3-pentafluoropropane ALLIEDSIGNAL INC. (US) 1999-03-09 US claimed
EP-0711266-A1 PROCESS FOR THE PREPARATION OF HYDROFLUOROCARBONS HAVING 3 TO 7 CARBON ATOMS AlliedSignal Inc. (US) 1996-05-15 EP claimed
WO-1995004021-A1 PROCESS FOR THE PREPARATION OF HYDROFLUOROCARBONS HAVING 3 TO 7 CARBON ATOMS ALLIEDSIGNAL INC. (US) 1995-02-09 WO claimed
US-5315048-A Preparation of 1,1,1,2,3-pentafluoropropane by reduction of 1,2,3-trichloropentafluropropane ALLIEDSIGNAL INC. (US) 1994-05-24 US claimed
EP-0490147-A2 Preparing isomer free 1,1-dichloro-2,2,3,3,3-pentafluoropropane HALOCARBON PRODUCTS CORPORATION (US) 1992-06-17 EP claimed
EP-0436031-A1 PROCESS FOR PRODUCING A DICHLOROPENTAFLUOROPROPANE ASAHI GLASS COMPANY LTD. (JP) 1991-07-10 EP claimed
WO-1991001287-A1 PROCESS FOR PRODUCING A DICHLOROPENTAFLUOROPROPANE ASAHI GLASS COMPANY LTD. (JP) 1991-02-07 WO claimed
US-4634546-A Process for the intercalation of graphitic carbon employing fully halogenated hydrocarbons CELANESE CORPORATION (US) 1987-01-06 US claimed
US-4438088-A Preparation of antimony trifluorodichloride and fluorination of fluorinatable hydrocarbons and halocarbons therewith THE DOW CHEMICAL COMPANY (US) 1984-03-20 US claimed
JP-4266835-A None JP disclosed
JP-61118333-A None JP disclosed
US-4241137-A AGITATING IN WATER AND AN ALIPHATIC HYDROCARBON, AN AROMATIC HYDROCARBON, AN ETHER, OR AN ORGANIC FLUORINE COMPOUND; AGGLOMERATION TOA MOLDABLE POWDER DAIKIN KOGYO CO., LTD. (JP) 1980-12-23 US disclosed
US-3953585-A Manufacture of oxygen difluoride ALLIED CHEMICAL CORPORATION (US) 1976-04-27 US disclosed