Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 5/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.31 |
| ▸ | AMPD3 | Q01432 | 2/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688919 | 0.76 | AHCY (0.45) | ADAADORA3ADORA2B | |
| SCHEMBL9690886 | 0.76 | AHCY (0.45) | ADAADORA3ADORA2B | |
| SCHEMBL10448915 | 0.76 | AHCY (0.45) | ADAADORA3ADORA2B | |
| SCHEMBL13842628 | 0.75 | ALDH1A1 (0.45) | ADAADORA3ADORA2AADORA1AMPD3 | |
| SCHEMBL21133144 | 0.75 | ALDH1A1 (0.45) | ADAADORA3ADORA2AADORA1AMPD3 | |
| SCHEMBL8373036 | 0.75 | ALDH1A1 (0.45) | ADAADORA3ADORA2AADORA1AMPD3 | |
| SCHEMBL12826634 | 0.75 | ALDH1A1 (0.45) | ADAADORA3ADORA2AADORA1AMPD3 | |
| Pentostatin SCHEMBL21133143 | 0.74 | ADA (0.57) | ADAADORA3ADORA2AADORA1 | |
| Pentostatin SCHEMBL7715689 | 0.74 | ADA (0.57) | ADAADORA3ADORA2AADORA1 | |
| Pentostatin SCHEMBL7790216 | 0.74 | ADA (0.57) | ADAADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110245484-A1 | STEREOSELECTIVE SYNTHESIS OF PHOSPHORUS CONTAINING ACTIVES | PHARMASSET, INC. (US) | 2011-10-06 | — | — | US | disclosed |
| US-7393954-B2 | Process for the production of pentostatin aglycone and pentostatin | RELIABLE BIOPHARMACEUTICAL CORPORATION (US) | 2008-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245484-A1 | STEREOSELECTIVE SYNTHESIS OF PHOSPHORUS CONTAINING ACTIVES | PPA1, ENPP1, ITPA | ADA 329/4885ADORA3 1334/4885ADORA2A 780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.