Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.54 |
| ▸ | CASP6 | P55212 | 2/20 | 0.54 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2565715 | 0.83 | F2 (0.51) | TDP1L3MBTL1KMT2AF2MEN1 | |
| SCHEMBL2565712 | 0.81 | F2 (0.50) | TDP1L3MBTL1KMT2ARAB9AF2 | |
| SCHEMBL7049647 | 0.80 | MAPT (0.60) | L3MBTL1MAPTALDH1A1 | |
| SCHEMBL15506017 | 0.80 | ALDH1A1 (0.60) | KMT2AMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL11323189 | 0.80 | MAPT (0.56) | RAB9AMAPTALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL7053170 | 0.79 | MAPT (0.58) | L3MBTL1KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL12376720 | 0.79 | F2 (0.57) | TDP1KMT2AF2MEN1ALDH1A1 | |
| SCHEMBL12561256 | 0.79 | HDAC1 (0.55) | TDP1KMT2AMAPTF2MEN1 | |
| SCHEMBL2282162 | 0.78 | KMT2A (0.53) | KMT2AF2MEN1ALDH1A1HPGD | |
| SCHEMBL11606625 | 0.77 | ALDH1A1 (0.55) | TDP1L3MBTL1KMT2ARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069286-B1 | INHIBITORS FOR GLYT-1 | HOFFMANN LA ROCHE (CH) | 2012-09-19 | — | — | EP | claimed |
| EP-2069286-B1 | INHIBITORS FOR GLYT-1 | HOFFMANN LA ROCHE (CH) | 2012-09-19 | — | — | EP | disclosed |