SCHEMBL122373

SCHEMBL122373

CC(=O)Nc1ccc(C)c(NS(=O)(=O)C(F)(F)F)c1

nearest known ligand 0.66

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.66
SMN1; SMN2 Q16637 1/20 0.66
KMT2A Q03164 2/20 0.51
IDH1 O75874 2/20 0.50
CYP2C9 P11712 1/20 0.49
TSHR P16473 1/20 0.49
ALDH1A1 P00352 2/20 0.49
PKM P14618 2/20 0.48
PTGS1 P23219 3/20 0.47
PTGS2 P35354 3/20 0.47
NPC1 O15118 1/20 0.44
MAPT P10636 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
RECQL P46063 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11511786 0.99 MAPK1 (0.64) MAPK1SMN1; SMN2KMT2AIDH1CYP2C9
Diethanolamine SCHEMBL31349864 0.90 MAPK1 (0.54) MAPK1SMN1; SMN2KMT2AIDH1CYP2C9
SCHEMBL11010144 0.89 MAPK1 (0.66) MAPK1SMN1; SMN2KMT2AIDH1CYP2C9
SCHEMBL7039101 0.85 NPC1 (0.47) MAPK1SMN1; SMN2KMT2ACYP2C9TSHR
SCHEMBL55691 0.81 MAPK1 (0.54) MAPK1SMN1; SMN2KMT2AIDH1ALDH1A1
SCHEMBL8537382 0.81 MAPK1 (0.54) MAPK1SMN1; SMN2KMT2AIDH1ALDH1A1
Potassium SCHEMBL29827207 0.79 MAPK1 (0.53) MAPK1SMN1; SMN2KMT2AIDH1ALDH1A1
SCHEMBL31725340 0.78 KMT2A (0.65) SMN1; SMN2KMT2ATSHRALDH1A1PKM
SCHEMBL8716883 0.78 KMT2A (0.65) SMN1; SMN2KMT2ATSHRALDH1A1PKM
SCHEMBL3239869 0.78 L3MBTL1 (0.62) MAPK1SMN1; SMN2KMT2AIDH1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1836 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 EP claimed
EP-3578541-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY, AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-05-28 EP claimed
US-20240138408-A1 COMPOSITION COMPRISING BENZYLAMINE ACARICIDE AND USE THEREOF SHANGDONG KANGIAO BIO-TECHNOLOGY CO., LTD (CN) 2024-05-02 US claimed
US-20230292757-A1 SYNERGISTIC AGROCHEMICAL COMPOSITION COMPRISING DIAMIDES AND PLANT GROWTH REGULATORS RAJDHANI PETROCHEMICALS PRIVATE LIMITED (IN) 2023-09-21 US claimed
EP-3407717-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2021-07-28 EP claimed
EP-3407716-B9 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2021-07-14 EP claimed
EP-3407720-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2021-03-10 EP claimed
EP-3408263-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2021-03-03 EP claimed
US-20100035753-A1 Fungicidal Mixtures Comprising Substituted 1-methylpyrazol-4-ylcarboxanilides BASF SE (DE) 2010-02-11 US claimed
CN-101631465-A Fungicidal mixtures comprising substituted 1-methylpyrazol-4-ylcarboxanilides BASF SE 2010-01-20 CN claimed
EP-2061320-A2 FUNGICIDAL MIXTURES COMPRISING SUBSTITUTED 1-METHYLPYRAZOL-4-YLCARBOXANILIDES BASF SE (DE) 2009-05-27 EP claimed
US-20090054237-A1 COMPOSITIONS AND METHODS SYNGENTA CROP PROTECTION, INC. (US) 2009-02-26 US claimed
WO-2008095890-A2 FUNGICIDAL MIXTURES COMPRISING SUBSTITUTED 1-METHYLPYRAZOL-4-YLCARBOXANILIDES BASF SE (DE) 2008-08-14 WO claimed
CN-101203131-A Compositions and methods SYNGENTA PARTICIPATIONS AG (CH) 2008-06-18 CN claimed
EP-1895838-A1 COMPOSITIONS AND METHODS Syngeta Participations AG (CH) 2008-03-12 EP claimed
WO-2007001919-A1 COMPOSITIONS AND METHODS SYNGENTA PARTICIPATIONS AG (CH) 2007-01-04 WO claimed
US-4163659-A HERBICIDES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1979-08-07 US claimed
US-4076519-A N-substituted perfluoroalkanesulfonamides as herbicides MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-02-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100035753-A1 Fungicidal Mixtures Comprising Substituted 1-methylpyrazol-4-ylcarboxanilides CBR3, CBR1, HCN2 MAPK1 2782/4885SMN1; SMN2 3901/4885KMT2A 1943/4885
US-20240138408-A1 COMPOSITION COMPRISING BENZYLAMINE ACARICIDE AND USE THEREOF BCHE, AAAS, BROX MAPK1 3842/4885SMN1; SMN2 477/4885KMT2A 1304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.