Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 16/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1223900 | 1.00 | KCNH2 (0.37) | KCNH2DRD2DRD4NR3C2 | |
| SCHEMBL3667724 | 0.85 | KCNH2 (0.37) | KCNH2 | |
| SCHEMBL1224363 | 0.84 | KCNH2 (0.39) | KCNH2 | |
| SCHEMBL1223105 | 0.84 | KCNH2 (0.39) | KCNH2 | |
| SCHEMBL3666412 | 0.78 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL1224376 | 0.77 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL1224378 | 0.77 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL1223940 | 0.75 | DRD2 (0.42) | KCNH2DRD2DRD4 | |
| SCHEMBL1223298 | 0.75 | DRD2 (0.42) | KCNH2DRD2DRD4 | |
| SCHEMBL1223112 | 0.75 | KCNH2 (0.35) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110039823-A1 | OXAZOLIDINONE ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-02-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039823-A1 | OXAZOLIDINONE ANTIBIOTICS | OXA1L, XDH, UBE2D3 | KCNH2 912/4885DRD2 78/4885DRD4 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.