Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 4/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12239059 | 0.94 | BDKRB1 (0.53) | BDKRB1CNR1MMP13MAPK14CYP3A4 | |
| SCHEMBL2547691 | 0.93 | BDKRB1 (0.53) | BDKRB1CNR1PPARD | |
| SCHEMBL10121264 | 0.91 | BDKRB1 (0.49) | BDKRB1CNR1MAPK14CYP3A4HTT | |
| SCHEMBL765537 | 0.91 | BDKRB1 (0.54) | BDKRB1CNR1MMP13MAPK14CYP3A4 | |
| SCHEMBL765652 | 0.90 | BDKRB1 (0.49) | BDKRB1CNR1SMN1; SMN2PPARDCARM1 | |
| SCHEMBL10121356 | 0.90 | BDKRB1 (0.48) | BDKRB1CNR1PPARDCARM1PRMT6 | |
| SCHEMBL12262806 | 0.89 | BDKRB1 (0.55) | BDKRB1CNR1PPARDCXCR4 | |
| SCHEMBL12239073 | 0.89 | BDKRB1 (0.47) | BDKRB1CNR1 | |
| SCHEMBL12239074 | 0.89 | BDKRB1 (0.49) | BDKRB1CNR1CARM1PRMT6 | |
| SCHEMBL764420 | 0.88 | BDKRB1 (0.48) | BDKRB1CNR1PPARDCARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8916589-B2 | Bradykinin B1-antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-12-23 | — | — | US | disclosed |
| US-20110263626-A1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263626-A1 | NOVEL BRADYKININ B1-ANTAGONISTS | BDKRB1, BDKRB2, EDNRB | BDKRB1 1/4885CNR1 72/4885MMP13 3730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.