Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 8/20 | 0.47 |
| ▸ | CNR1 | P21554 | 6/20 | 0.41 |
| ▸ | WDR5 | P61964 | 5/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10121221 | 0.92 | BDKRB1 (0.47) | BDKRB1CNR1WDR5 | |
| SCHEMBL12239072 | 0.89 | BDKRB1 (0.51) | BDKRB1CNR1 | |
| SCHEMBL10121264 | 0.89 | BDKRB1 (0.49) | BDKRB1CNR1 | |
| SCHEMBL2547691 | 0.87 | BDKRB1 (0.53) | BDKRB1CNR1 | |
| SCHEMBL765652 | 0.86 | BDKRB1 (0.49) | BDKRB1CNR1 | |
| SCHEMBL12239074 | 0.86 | BDKRB1 (0.49) | BDKRB1CNR1 | |
| SCHEMBL764420 | 0.86 | BDKRB1 (0.48) | BDKRB1CNR1 | |
| SCHEMBL12239059 | 0.85 | BDKRB1 (0.53) | BDKRB1CNR1 | |
| SCHEMBL765524 | 0.85 | BDKRB1 (0.51) | BDKRB1CNR1 | |
| SCHEMBL765522 | 0.85 | BDKRB1 (0.50) | BDKRB1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8916589-B2 | Bradykinin B1-antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-12-23 | — | — | US | disclosed |
| US-20110263626-A1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263626-A1 | NOVEL BRADYKININ B1-ANTAGONISTS | BDKRB1, BDKRB2, EDNRB | BDKRB1 1/4885CNR1 72/4885WDR5 2956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.