Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.42 |
| ▸ | SCN1A | P35498 | 2/20 | 0.42 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12239161 | 0.91 | POLB (0.46) | SMN1; SMN2POLBSCDGPR119HRH3 | |
| SCHEMBL12262498 | 0.90 | SCN8A (0.42) | SMN1; SMN2SCDGPR119MEN1NPC1 | |
| SCHEMBL1007710 | 0.90 | UTS2R (0.47) | UTS2R | |
| Hydrochloric Acid SCHEMBL1006064 | 0.89 | UTS2R (0.47) | SMN1; SMN2MEN1NPC1TP53HPGD | |
| SCHEMBL12239186 | 0.89 | SCD (0.42) | SMN1; SMN2SCDGPR119MEN1NPC1 | |
| SCHEMBL12239160 | 0.89 | POLB (0.44) | SMN1; SMN2POLBSCDHRH3CSNK2A1 | |
| SCHEMBL12239188 | 0.88 | GPR119 (0.42) | SMN1; SMN2SCDGPR119MEN1NPC1 | |
| SCHEMBL1003945 | 0.88 | SCN1A (0.41) | SMN1; SMN2SCDGPR119MEN1NPC1 | |
| SCHEMBL1007986 | 0.88 | UTS2R (0.41) | SMN1; SMN2SCDGPR119MEN1NPC1 | |
| SCHEMBL12239159 | 0.88 | SCD (0.49) | SMN1; SMN2POLBSCDMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263557-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263557-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | GPR119, GPR55, NR1H2 | SMN1; SMN2 3819/4885POLB 4770/4885SCD 1145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.