Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 18/20 | 0.61 |
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2532942 | 0.88 | MET (0.76) | METNQO2 | |
| SCHEMBL12240062 | 0.82 | MET (0.64) | METNQO2 | |
| SCHEMBL12240064 | 0.82 | MET (0.58) | METNQO2 | |
| SCHEMBL13285275 | 0.81 | MET (0.59) | METNQO2HDAC1 | |
| SCHEMBL13180922 | 0.80 | MET (0.64) | METNQO2 | |
| SCHEMBL13284451 | 0.79 | MET (0.59) | METNQO2HDAC1 | |
| SCHEMBL13285273 | 0.79 | MET (0.59) | METNQO2 | |
| SCHEMBL13180936 | 0.79 | MET (0.55) | METNQO2 | |
| SCHEMBL12239832 | 0.79 | MET (0.55) | METNQO2 | |
| SCHEMBL13285174 | 0.79 | MET (0.55) | METNQO2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110257181-A1 | PYRIDAZINONE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257181-A1 | PYRIDAZINONE DERIVATIVES | MET, TYRO3, ERBB2 | MET 1/4885NQO2 600/4885HDAC1 1706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.