⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1901029 | 0.81 | — | — | |
| SCHEMBL5458009 | 0.74 | — | — | |
| SCHEMBL7337430 | 0.74 | — | — | |
| SCHEMBL6373455 | 0.74 | — | — | |
| SCHEMBL27423110 | 0.72 | — | — | |
| SCHEMBL2073974 | 0.71 | — | — | |
| SCHEMBL2458402 | 0.70 | — | — | |
| SCHEMBL243363 | 0.70 | — | — | |
| SCHEMBL4048541 | 0.70 | — | — | |
| SCHEMBL4039262 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2358 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113967258-B | FAP-activated therapeutic agents and related uses | 塔夫茨大学信托人 | 2024-07-02 | — | — | CN | claimed |
| CN-116981479-A | FAP-activated radiation therapy diagnostic method and use relating thereto | 塔夫茨大学信托人 | 2023-10-31 | — | — | CN | claimed |
| EP-4262878-A1 | FAP-ACTIVATED RADIOTHERANOSTICS, AND USES RELATED THERETO | TRUSTEES OF TUFTS COLLEGE (US) | 2023-10-25 | — | — | EP | claimed |
| US-20230265111-A1 | BORONATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-08-24 | — | — | US | claimed |
| US-11667638-B2 | 4-substitued cytisine analogues | THE UNIVERSITY OF BRISTOL | 2023-06-06 | — | — | US | claimed |
| CN-107090014-B | Stabilized liquid enzyme compositions | 诺维信公司 | 2023-04-25 | — | — | CN | claimed |
| EP-4144354-A1 | FAP-ACTIVATED PROTEASOME INHIBITORS FOR TREATING SOLID TUMORS | Trustees Of Tufts College (US) | 2023-03-08 | — | — | EP | claimed |
| EP-4112620-A1 | CYTISINE DERIVATIVES FOR THE TREATMENT OF ADDICTION | The University of Bristol (GB) | 2023-01-04 | — | — | EP | claimed |
| US-20220211883-A1 | FAP-ACTIVATED RADIOTHERANOSTICS AND USES RELATED THERETO | TRUSTEES OF TUFTS COLLEGE | 2022-07-07 | — | — | US | claimed |
| WO-2022133288-A1 | FAP-ACTIVATED RADIOTHERANOSTICS, AND USES RELATED THERETO | TRUSTEES OF TUFTS COLLEGE (US) | 2022-06-23 | — | — | WO | claimed |
| EP-0364344-A2 | Novel peptidase inhibitors | MERRELL PHARMACEUTICALS INC. (US) | 1990-04-18 | — | — | EP | claimed |
| EP-0363284-A2 | Use of peptidase inhibitors for the preparation of medicaments useful for the treatment of strokes | MERRELL PHARMACEUTICALS INC. (US) | 1990-04-11 | — | — | EP | claimed |
| EP-0362002-A1 | HIV protease inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-04-04 | — | — | EP | claimed |
| EP-0356595-A1 | Novel peptidase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-03-07 | — | — | EP | claimed |
| EP-0275101-A2 | Novel peptidase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-07-20 | — | — | EP | claimed |
| EP-0272671-A2 | Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors | SANDOZ LTD. (CH) | 1988-06-29 | — | — | EP | claimed |
| CN-86101268-A | The preparation method of new peptidase inhibitors | — | 1987-02-04 | — | — | CN | claimed |
| EP-0195212-A2 | Novel peptidase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-09-24 | — | — | EP | claimed |
| US-4518528-A | α Amino fluoro ketones | MP BIOMEDICALS, LLC | 1985-05-21 | — | — | US | claimed |
| EP-0130679-A2 | Alpha amino fluoro ketones | ENZYME SYSTEMS PRODUCTS INC. (US) | 1985-01-09 | — | — | EP | claimed |