Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGAM1 | P18669 | 2/20 | 0.47 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.44 |
| ▸ | ACSL6 | Q9UKU0 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15759331 | 0.94 | ACSL1 (0.48) | PGAM1ACSL1ACSL6KDM4EALDH1A1 | |
| SCHEMBL12240936 | 0.88 | KDM4E (0.54) | ACSL1ACSL6KDM4EALDH1A1HPGD | |
| SCHEMBL12240974 | 0.87 | KDM4E (0.43) | ACSL1ACSL6KDM4EALDH1A1HPGD | |
| SCHEMBL12240964 | 0.86 | XDH (0.54) | ACSL1ACSL6KDM4EALDH1A1HPGD | |
| SCHEMBL1798063 | 0.82 | NPC1 (0.57) | ACSL1ACSL6KDM4EALDH1A1HPGD | |
| SCHEMBL12240977 | 0.81 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDMAPTRAB9A | |
| SCHEMBL15759343 | 0.80 | ACSL1 (0.46) | ACSL1ACSL6KDM4EALDH1A1HPGD | |
| SCHEMBL15759330 | 0.79 | ACSL1 (0.54) | ACSL1ACSL6KDM4EALDH1A1HPGD | |
| SCHEMBL12240985 | 0.78 | KDM4E (0.54) | ACSL1ACSL6KDM4EALDH1A1HPGD | |
| SCHEMBL8657871 | 0.76 | ACSL1 (0.67) | ACSL1ACSL6KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8741659-B2 | Composition for measuring the binding affinity between nucleic acid and test substance, and use thereof | OSAKA UNIVERSITY (JP) | 2014-06-03 | — | — | US | disclosed |
| US-20120238029-A1 | COMPOSITION FOR MEASURING THE BINDING AFFINITY BETWEEN NUCLEIC ACID AND TEST SUBSTANCE, AND USE THEREOF | OSAKA UNIVERSITY (JP) | 2012-09-20 | — | — | US | disclosed |
| US-20110263041-A1 | COMPOSITION FOR MEASURING THE BINDING AFFINITY BETWEEN NUCLEIC ACID AND TEST SUBSTANCE, AND USE THEREOF | OSAKA UNIVERSITY (JP) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263041-A1 | COMPOSITION FOR MEASURING THE BINDING AFFINITY BETWEEN NUCLEIC ACID AND TEST SUBSTANCE, AND USE THEREOF | RBM3, HNRNPA3, HNRNPAB | PGAM1 3611/4885ACSL1 3918/4885ACSL6 4130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.