Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 5/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21789271 | 0.80 | JAK1 (0.45) | KMT2AL3MBTL1BTKJAK1CTSK | |
| SCHEMBL1928948 | 0.76 | NFKB1 (0.56) | NFKB1NFKB2RELAKMT2AL3MBTL1 | |
| SCHEMBL27635798 | 0.74 | NFKB1 (0.48) | NFKB1NFKB2RELAKMT2AL3MBTL1 | |
| SCHEMBL3302438 | 0.71 | CPB1 (0.46) | KMT2AL3MBTL1CTSKKDM1AMAOB | |
| SCHEMBL27621671 | 0.70 | NFKB1 (0.44) | NFKB1NFKB2RELAKMT2AL3MBTL1 | |
| SCHEMBL27621669 | 0.70 | NFKB1 (0.44) | NFKB1NFKB2RELAKMT2AL3MBTL1 | |
| SCHEMBL31390591 | 0.70 | CHRM2 (0.48) | HSD11B1GPR119 | |
| SCHEMBL1927425 | 0.69 | NFKB1 (0.51) | NFKB1NFKB2RELAKMT2AL3MBTL1 | |
| SCHEMBL17473176 | 0.69 | NFKB1 (0.43) | NFKB1NFKB2RELAKMT2AL3MBTL1 | |
| SCHEMBL5202686 | 0.68 | NFKB1 (0.50) | NFKB1NFKB2RELAKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884118-B2 | such as 1-Cyclopentyl-5-iodotetrazole, suitable as microbicides for protecting plants and materials | LANXESS DEUTSCHLAND GMBH (DE) | 2011-02-08 | — | — | US | disclosed |
| US-20090042960-A1 | 1-Cycloalkyl-5-Iodotetrazoles | LANXESS DEUTSCHLAND GMBH (DE) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042960-A1 | 1-Cycloalkyl-5-Iodotetrazoles | MSR1, CYP51A1, MCL1 | NFKB1 1029/4885NFKB2 2197/4885RELA 2394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.