Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PBK | Q96KB5 | 2/20 | 0.46 |
| ▸ | CYP8B1 | Q9UNU6 | 1/20 | 0.46 |
| ▸ | AKT2 | P31751 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.44 |
| ▸ | SSTR2 | P30874 | 3/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1224810 | 1.00 | CHRM4 (0.55) | CHRM4PIK3CACYP2C19PBKCYP8B1 | |
| SCHEMBL1223880 | 0.92 | CHRM4 (0.60) | CHRM4PIK3CACYP2C19CYP8B1AKT2 | |
| SCHEMBL24018033 | 0.81 | CHRM4 (0.48) | CHRM4PIK3CACYP8B1NCF1CCNC | |
| SCHEMBL1224243 | 0.81 | CDK8 (0.48) | PIK3CACYP2C19PBKCYP8B1AKT2 | |
| SCHEMBL1223420 | 0.81 | NCF1 (0.62) | CHRM4PIK3CACYP2C19PBKHRH4 | |
| SCHEMBL1223418 | 0.81 | NCF1 (0.62) | CHRM4PIK3CACYP2C19PBKHRH4 | |
| SCHEMBL1224246 | 0.81 | CDK8 (0.48) | PIK3CACYP2C19PBKCYP8B1AKT2 | |
| SCHEMBL5137952 | 0.81 | NCF1 (0.56) | PIK3CACYP2C19PBKAKT2HRH4 | |
| SCHEMBL17729980 | 0.81 | CHRM4 (0.56) | CHRM4PIK3CACYP8B1AKT2ROCK2 | |
| SCHEMBL20935457 | 0.79 | CHRM4 (0.54) | CHRM4PIK3CACYP8B1AKT2NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2915813-B1 | Oxazolidinone antibiotics | ACTELION PHARMACEUTICALS LTD (CH) | 2017-02-01 | — | — | EP | disclosed |
| EP-2915813-A1 | Oxazolidinone antibiotics | Actelion Pharmaceuticals Ltd. (CH) | 2015-09-09 | — | — | EP | disclosed |
| EP-2905283-A1 | Oxazolidinone antibiotics | Actelion Pharmaceuticals Ltd. (CH) | 2015-08-12 | — | — | EP | disclosed |
| US-8217029-B2 | Oxazolidinone antibiotics | ACTELION PHARMACEUTICALS LTD (CH) | 2012-07-10 | — | — | US | disclosed |
| US-20110039823-A1 | OXAZOLIDINONE ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039823-A1 | OXAZOLIDINONE ANTIBIOTICS | OXA1L, XDH, UBE2D3 | CHRM4 1317/4885PIK3CA 3947/4885CYP2C19 620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.