SCHEMBL12249136

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12248439	0.91	MAPT (0.56)	PARP1MAPTKDM4AKDM4BKDM5B
	SCHEMBL15004093	0.91	PARP1 (0.53)	PARP1MAPTKDM4AKDM4BKDM5B
	SCHEMBL14994963	0.90	MAPT (0.55)	PARP1MAPTKDM4AKDM4BKDM5B
	SCHEMBL14992749	0.89	LMNA (0.55)	PARP1MAPTKDM4AKDM4BKDM5B
	SCHEMBL14995334	0.89	MAPT (0.57)	PARP1MAPTKDM4AKDM4BKDM5B
	SCHEMBL14995073	0.89	MAPT (0.54)	PARP1MAPTKDM4AKDM4BKDM5B
	SCHEMBL15133476	0.89	MAPT (0.56)	PARP1MAPTKDM4AKDM4BKDM5B
	SCHEMBL14994986	0.89	PARP1 (0.53)	PARP1MAPTADORA3LMNATSHR
	SCHEMBL12249709	0.88	ADORA3 (0.60)	PARP1MAPTKDM4AKDM4BKDM5B
	SCHEMBL12249028	0.88	PARP1 (0.72)	PARP1MAPTKDM4AKDM4BKDM5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.