Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13433620 | 0.80 | — | — | |
| SCHEMBL19478660 | 0.78 | CYP11B1 (0.31) | — | |
| SCHEMBL19850835 | 0.76 | — | — | |
| SCHEMBL17827795 | 0.76 | — | — | |
| SCHEMBL18030437 | 0.75 | — | — | |
| SCHEMBL13218909 | 0.75 | LPL (0.36) | — | |
| SCHEMBL16449382 | 0.75 | — | — | |
| SCHEMBL16546336 | 0.74 | — | — | |
| SCHEMBL16546370 | 0.74 | — | — | |
| SCHEMBL14328302 | 0.74 | RAPGEF4 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137154-B1 | PYRIDINE COMPOUNDS FOR LIQUID-CRYSTALLINE MIXTURES | MERCK PATENT GMBH (DE) | 2015-07-15 | — | — | EP | disclosed |
| US-8012547-B2 | Pyridine compounds for liquid-crystalline mixtures | MERCH PATENT GMBH (DE) | 2011-09-06 | — | — | US | disclosed |
| US-8012547-B2 | Pyridine compounds for liquid-crystalline mixtures | MERCH PATENT GMBH (DE) | 2011-09-06 | — | — | US | disclosed |
| US-20100127212-A1 | PYRIDINE COMPOUNDS FOR LIQUID-CRYSTALLINE MIXTURES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-05-27 | — | — | US | disclosed |
| US-20100127212-A1 | PYRIDINE COMPOUNDS FOR LIQUID-CRYSTALLINE MIXTURES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-05-27 | — | — | US | disclosed |
| WO-2008128622-A2 | PYRIDINE COMPOUNDS FOR LIQUID-CRYSTALLINE MIXTURES | MERCK PATENT GMBH (DE) | 2008-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100127212-A1 | PYRIDINE COMPOUNDS FOR LIQUID-CRYSTALLINE MIXTURES | CHRM1, CHRM2, CHRM4 | MEN1 600/4885KMT2A 3458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.