Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GRB2 | P62993 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.39 |
| ▸ | TPH1 | P17752 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29446290 | 0.85 | ANPEP (0.43) | BLMCYP2C19SMN1; SMN2GRB2ANPEP | |
| SCHEMBL7960935 | 0.84 | SLC7A5 (0.48) | GRB2EPHX2PTPN1TPH1 | |
| SCHEMBL14043511 | 0.84 | GRB2 (0.41) | BLMCYP2C19SMN1; SMN2GRB2ANPEP | |
| SCHEMBL12234262 | 0.83 | GRB2 (0.40) | BLMCYP2C19GRB2ANPEPLAP3 | |
| SCHEMBL3626587 | 0.82 | PTPRC (0.57) | BLMSMN1; SMN2GRB2ANPEPLAP3 | |
| SCHEMBL14365819 | 0.82 | ANPEP (0.45) | BLMCYP2C19SMN1; SMN2GRB2ANPEP | |
| SCHEMBL4066744 | 0.82 | PTPRC (0.57) | BLMSMN1; SMN2GRB2ANPEPLAP3 | |
| SCHEMBL273663 | 0.82 | PTPRC (0.57) | BLMSMN1; SMN2GRB2ANPEPLAP3 | |
| SCHEMBL1152 | 0.82 | PTPRC (0.57) | BLMSMN1; SMN2GRB2ANPEPLAP3 | |
| SCHEMBL5269148 | 0.82 | ANPEP (0.45) | BLMCYP2C19SMN1; SMN2GRB2ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263539-A1 | SHIP 1 MODULATOR COMPOUNDS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2011-10-27 | — | — | US | disclosed |
| US-20100323990-A1 | SHIP 1 MODULATOR PRODRUGS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2010-12-23 | — | — | US | disclosed |
| US-20100168225-A1 | Small-Molecule Hepatitis C Virus (HCV) NS3/4A Serine Protease Inhibitors | JEAN FRANCOIS | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168225-A1 | Small-Molecule Hepatitis C Virus (HCV) NS3/4A Serine Protease Inhibitors | SRR, HAVCR2, CBR3 | BLM 3231/4885CYP2C19 1012/4885SMN1; SMN2 3627/4885 |
| US-20100323990-A1 | SHIP 1 MODULATOR PRODRUGS | PPM1D, PPM1G, PPM1F | BLM 4471/4885CYP2C19 1979/4885SMN1; SMN2 2604/4885 |
| US-20110263539-A1 | SHIP 1 MODULATOR COMPOUNDS | PPM1F, PPM1D, PPP1R1B | BLM 4175/4885CYP2C19 4018/4885SMN1; SMN2 2765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.