Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825990 | 0.81 | CA1 (0.32) | KMT2ATRIM24TRIM33CA1CA2 | |
| SCHEMBL13125935 | 0.73 | KMT2A (0.46) | KMT2ATRIM24TRIM33ALDH1A1CA1 | |
| SCHEMBL6764761 | 0.71 | KMT2A (0.56) | KMT2ATRIM24TRIM33ALDH1A1CA1 | |
| SCHEMBL7706356 | 0.71 | KMT2A (0.56) | KMT2ATRIM24TRIM33ALDH1A1CA1 | |
| SCHEMBL5336897 | 0.71 | CA1 (0.40) | KMT2AALDH1A1CA1CA2CA4 | |
| SCHEMBL14249873 | 0.69 | KMT2A (0.48) | KMT2ATRIM24TRIM33ALDH1A1CA1 | |
| SCHEMBL11079654 | 0.69 | — | — | |
| SCHEMBL13811044 | 0.69 | CA1 (0.43) | KMT2ATRIM24TRIM33ALDH1A1CA1 | |
| SCHEMBL3796373 | 0.69 | CA1 (0.43) | KMT2ATRIM24TRIM33ALDH1A1CA1 | |
| SCHEMBL13811067 | 0.69 | CA1 (0.57) | KMT2ATRIM24TRIM33ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10696686-B2 | Herbicidally active (alkynyl-phenyl)-substituted cyclic dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2020-06-30 | — | — | US | disclosed |
| US-10590143-B2 | Herbicidally active (alkynyl-phenyl)-substituted cyclic dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2020-03-17 | — | — | US | disclosed |
| EP-3004052-B1 | HERBICIDALLY ACTIVE (ALKYNYL-PHENYL)-SUBSTITUTED CYCLIC DIONE COMPOUNDS AND DERIVATIVES THEREOF | SYNGENTA LTD (GB) | 2018-04-18 | — | — | EP | disclosed |
| EP-3004043-B1 | HERBICIDALLY ACTIVE (ALKYNYL-PHENYL)-SUBSTITUTED CYCLIC DIONE COMPOUNDS AND DERIVATIVES THEREOF | SYNGENTA LTD (GB) | 2018-01-31 | — | — | EP | disclosed |
| EP-2785181-B1 | 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS, AND DERIVATIVES THEREOF | SYNGENTA LTD (GB) | 2016-08-17 | — | — | EP | disclosed |
| US-20160207934-A1 | Herbicidally active (alkynyl-phenyl)-substituted cyclic dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2016-07-21 | — | — | US | disclosed |
| US-20160143277-A1 | Herbicidally Active (alkynyl-phenyl)-Substituted Cyclic Dione Compounds and Derivatives Thereof | SYNGENTA LIMITED (GB) | 2016-05-26 | — | — | US | disclosed |
| EP-3004052-A1 | HERBICIDALLY ACTIVE (ALKYNYL-PHENYL)-SUBSTITUTED CYCLIC DIONE COMPOUNDS AND DERIVATIVES THEREOF | Syngenta Limited (GB) | 2016-04-13 | — | — | EP | disclosed |
| EP-3004043-A1 | HERBICIDALLY ACTIVE (ALKYNYL-PHENYL)-SUBSTITUTED CYCLIC DIONE COMPOUNDS AND DERIVATIVES THEREOF | Syngenta Limited (GB) | 2016-04-13 | — | — | EP | disclosed |
| US-9107415-B2 | 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds, and derivatives thereof | SYNGENTA PARTICPATIONS AG (CH) | 2015-08-18 | — | — | US | disclosed |
| WO-2012059436-A2 | PHENYL-SUBSTITUTED BICYCLOOCTANE-1,3-DIONE-DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2012-05-10 | — | — | WO | disclosed |
| CN-102264226-A | Phenyl-substituted bicyclooctane-1,3-dione derivatives | — | 2011-11-30 | — | — | CN | disclosed |
| CN-102264226-A | Phenyl-substituted bicyclooctane-1,3-dione derivatives | — | 2011-11-30 | — | — | CN | disclosed |
| EP-2334175-A2 | PHENYL-SUBSTITUTED BICYCLOOCTANE-1,3-DIONE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-06-22 | — | — | EP | disclosed |
| US-20110039701-A1 | Phenyl-substituted Bicyclooctane-1,3-dione Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-02-17 | — | — | US | disclosed |
| US-20110039701-A1 | Phenyl-substituted Bicyclooctane-1,3-dione Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-02-17 | — | — | US | disclosed |
| US-20110039701-A1 | Phenyl-substituted Bicyclooctane-1,3-dione Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-02-17 | — | — | US | disclosed |
| US-20100298145-A1 | Spiroheterocyclic Tetronic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2010-11-25 | — | — | US | disclosed |
| WO-2010040460-A3 | PHENYL-SUBSTITUTED BICYCLOOCTANE-1,3-DIONE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-09-23 | — | — | WO | disclosed |
| WO-2010040460-A2 | PHENYL-SUBSTITUTED BICYCLOOCTANE-1,3-DIONE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039701-A1 | Phenyl-substituted Bicyclooctane-1,3-dione Derivatives | DDT, PIP5K1B, PIP5K1C | KMT2A 2664/4885TRIM24 4544/4885TRIM33 4007/4885 |
| US-10696686-B2 | Herbicidally active (alkynyl-phenyl)-substituted cyclic dione compounds and derivatives thereof | DDT, CNPY2, CNPY3 | KMT2A 198/4885TRIM24 4657/4885TRIM33 4100/4885 |
| US-20160207934-A1 | Herbicidally active (alkynyl-phenyl)-substituted cyclic dione compounds and derivatives thereof | DDT, CNPY2, CNPY3 | KMT2A 198/4885TRIM24 4657/4885TRIM33 4100/4885 |
| US-20160143277-A1 | Herbicidally Active (alkynyl-phenyl)-Substituted Cyclic Dione Compounds and Derivatives Thereof | DDT, CNPY2, TET1 | KMT2A 191/4885TRIM24 4546/4885TRIM33 3753/4885 |
| US-20100298145-A1 | Spiroheterocyclic Tetronic Acid Derivatives | DDT, PTPRG, WIZ | KMT2A 3670/4885TRIM24 4524/4885TRIM33 4644/4885 |
| US-10590143-B2 | Herbicidally active (alkynyl-phenyl)-substituted cyclic dione compounds and derivatives thereof | DDT, CNPY2, TET1 | KMT2A 191/4885TRIM24 4546/4885TRIM33 3753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.