SCHEMBL12259396

SCHEMBL12259396

CCCCCCCCCCCCN(CCCCCCCCCCCC)c1ccc2c(-c3c(Cl)cccc3Cl)c3ccc(=[N+](CCCCCCCCCCCC)CCCCCCCCCCCC)cc-3oc2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 0.43
▸ KMT2A Q03164 4/20 0.43
▸ TDP1 Q9NUW8 3/20 0.43
▸ BLM P54132 2/20 0.43
▸ THRB P10828 1/20 0.43
▸ RECQL P46063 1/20 0.43
▸ USP2 O75604 1/20 0.43
▸ POLB P06746 1/20 0.43
▸ PPARG P37231 1/20 0.43
▸ RXFP1 Q9HBX9 1/20 0.43
▸ NCOR2 Q9Y618 1/20 0.43
▸ TGM2 P21980 1/20 0.36
▸ P2RY6 Q15077 1/20 0.35
▸ FPR2 P25090 4/20 0.34
▸ SLC6A4 P31645 4/20 0.34
▸ SLC6A2 P23975 3/20 0.34
▸ SLC6A3 Q01959 3/20 0.34
▸ ALDH1A1 P00352 2/20 0.33
▸ HPGD P15428 2/20 0.33
▸ KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12259399 0.88 MEN1 (0.45) MEN1KMT2ATDP1BLMTHRB
SCHEMBL12259392 0.87 MEN1 (0.59) MEN1KMT2ATDP1BLMTHRB
SCHEMBL13295428 0.82 TGM2 (0.47) MEN1KMT2ATDP1BLMTHRB
SCHEMBL13295446 0.82 TGM2 (0.47) MEN1KMT2ATDP1BLMTHRB
SCHEMBL14046507 0.81 MEN1 (0.55) MEN1KMT2ATDP1BLMTHRB
SCHEMBL12259397 0.79 TGM2 (0.43) MEN1KMT2ATDP1BLMTHRB
SCHEMBL13932647 0.76 MEN1 (0.71) MEN1KMT2ATDP1BLMTHRB
SCHEMBL13918826 0.74 MEN1 (0.34) MEN1KMT2ABLMUSP2POLB
SCHEMBL13295448 0.74 MEN1 (0.48) MEN1KMT2ATDP1BLMTHRB
SCHEMBL13295432 0.74 MEN1 (0.48) MEN1KMT2ATDP1BLMTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9034920-B2 Fluorescent polymeric materials containing lipid soluble rhodamine dyes APPLIED BIOSYSTEMS, LLC (US) 2015-05-19 — — US disclosed
US-20140145115-A1 Fluorescent Polymeric Materials Containing Lipid Soluble Rhodamine Dyes APPLIED BIOSYSTEMS, LLC (US) 2014-05-29 — — US disclosed
US-20110226994-A1 Fluorescent Polymeric Materials Containing Lipid Soluble Rhodamine Dyes Life Technologies Corporation (US) 2011-09-22 — — US disclosed
US-20090072197-A1 FLUORESCENT POLYMERIC MATERIALS CONTAINING LIPID SOLUBLE RHODAMINE DYES APPLIED BIOSYSTEMS INC. (US) 2009-03-19 — — US disclosed
US-7432298-B2 Fluorescent polymeric materials containing lipid soluble rhodamine dyes APPLIED BIOSYSTEMS INC. (US) 2008-10-07 — — US disclosed
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