SCHEMBL12259399

SCHEMBL12259399

CCCCCCCCCCCCN(CCCCCCCCCCCC)c1ccc2c(-c3c(F)c(F)c(F)c(F)c3F)c3ccc(=[N+](CCCCCCCCCCCC)CCCCCCCCCCCC)cc-3oc2c1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.45
▸ BLM P54132 2/20 0.45
▸ KMT2A Q03164 2/20 0.45
▸ USP2 O75604 1/20 0.45
▸ POLB P06746 1/20 0.45
▸ PPARG P37231 1/20 0.45
▸ RXFP1 Q9HBX9 1/20 0.45
▸ NCOR2 Q9Y618 1/20 0.45
▸ THRB P10828 1/20 0.43
▸ RECQL P46063 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43
▸ P2RY6 Q15077 1/20 0.36
▸ FPR2 P25090 4/20 0.36
▸ TGM2 P21980 1/20 0.35
▸ SRC P12931 2/20 0.34
▸ CHRM1 P11229 1/20 0.33
▸ SLC6A4 P31645 4/20 0.32
▸ TLR7 Q9NYK1 1/20 0.32
▸ IGLV6-57 P01721 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12259396 0.88 MEN1 (0.43) MEN1BLMKMT2AUSP2POLB
SCHEMBL12259392 0.88 MEN1 (0.59) MEN1BLMKMT2AUSP2POLB
SCHEMBL13918826 0.86 MEN1 (0.34) MEN1BLMKMT2AUSP2POLB
SCHEMBL13295446 0.82 TGM2 (0.47) MEN1BLMKMT2AUSP2POLB
SCHEMBL13295428 0.82 TGM2 (0.47) MEN1BLMKMT2AUSP2POLB
SCHEMBL13932807 0.81 MEN1 (0.64) MEN1BLMKMT2AUSP2POLB
SCHEMBL14046582 0.80 MEN1 (0.56) MEN1BLMKMT2AUSP2POLB
SCHEMBL12259397 0.79 TGM2 (0.43) MEN1BLMKMT2AUSP2POLB
SCHEMBL13933225 0.76 MEN1 (0.71) MEN1BLMKMT2AUSP2POLB
SCHEMBL13295448 0.75 MEN1 (0.48) MEN1BLMKMT2AUSP2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9034920-B2 Fluorescent polymeric materials containing lipid soluble rhodamine dyes APPLIED BIOSYSTEMS, LLC (US) 2015-05-19 — — US disclosed
US-20140145115-A1 Fluorescent Polymeric Materials Containing Lipid Soluble Rhodamine Dyes APPLIED BIOSYSTEMS, LLC (US) 2014-05-29 — — US disclosed
US-20110226994-A1 Fluorescent Polymeric Materials Containing Lipid Soluble Rhodamine Dyes Life Technologies Corporation (US) 2011-09-22 — — US disclosed
US-20090072197-A1 FLUORESCENT POLYMERIC MATERIALS CONTAINING LIPID SOLUBLE RHODAMINE DYES APPLIED BIOSYSTEMS INC. (US) 2009-03-19 — — US disclosed
US-7432298-B2 Fluorescent polymeric materials containing lipid soluble rhodamine dyes APPLIED BIOSYSTEMS INC. (US) 2008-10-07 — — US disclosed
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