Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | MGLL | Q99685 | 3/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29376241 | 1.00 | POLB (0.50) | POLBMAPK1ATMFAAHMGLL | |
| SCHEMBL5393 | 1.00 | POLB (0.50) | POLBMAPK1ATMFAAHMGLL | |
| Phosphine SCHEMBL30259325 | 0.98 | POLB (0.48) | POLBMAPK1ATMFAAHMGLL | |
| Water SCHEMBL1042885 | 0.98 | POLB (0.48) | POLBMAPK1ATMFAAHMGLL | |
| Water SCHEMBL29441712 | 0.98 | POLB (0.48) | POLBMAPK1ATMFAAHMGLL | |
| Formic Acid SCHEMBL1091492 | 0.91 | POLB (0.43) | POLBMAPK1ATMFAAHMGLL | |
| SCHEMBL6639835 | 0.89 | POLB (0.70) | POLBMAPK1ATMFAAHMGLL | |
| SCHEMBL30273023 | 0.80 | POLB (0.38) | POLBMAPK1ATMDAOKDM4E | |
| Dicyclohexylcarbodiimide SCHEMBL14577062 | 0.78 | EPHX1 (0.39) | POLBMAPK1ATMFAAHMGLL | |
| SCHEMBL25400045 | 0.75 | FAAH (0.39) | POLBMAPK1ATMFAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2280025-A2 | New antitumoral compounds | Pharma Mar, S.A.U. (ES) | 2011-02-02 | — | — | EP | disclosed |
| EP-2280027-A2 | New antitumoral compounds | Pharma Mar, S.A.U. (ES) | 2011-02-02 | — | — | EP | disclosed |
| US-20070117743-A1 | New antitumoral compounds | PHARMA MAR, S.A.U. (ES) | 2007-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117743-A1 | New antitumoral compounds | BAK1, FOLH1, KLHL6 | POLB 4038/4885MAPK1 4180/4885ATM 2599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.