SCHEMBL12264019

SCHEMBL12264019

CNCc1ccc(C(=O)C(C)(C)N2CCOCC2)cc1

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.60
TSHR P16473 2/20 0.60
MAPK1 P28482 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
HRH3 Q9Y5N1 2/20 0.47
GAA P10253 1/20 0.44
KDM4E B2RXH2 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PKM P14618 1/20 0.40
MLYCD O95822 1/20 0.39
KMT2A Q03164 2/20 0.39
NCF1 P14598 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL306032 0.84 ALDH1A1 (0.65) ALDH1A1TSHRMAPK1SMN1; SMN2HRH3
SCHEMBL307240 0.83 ALDH1A1 (0.63) ALDH1A1TSHRMAPK1SMN1; SMN2HRH3
SCHEMBL3670808 0.82 ALDH1A1 (0.62) ALDH1A1TSHRMAPK1SMN1; SMN2HRH3
SCHEMBL8070009 0.82 ALDH1A1 (0.62) ALDH1A1TSHRMAPK1SMN1; SMN2HRH3
SCHEMBL9679493 0.81 ALDH1A1 (0.65) ALDH1A1TSHRMAPK1SMN1; SMN2HRH3
SCHEMBL12952339 0.81 ALDH1A1 (0.65) ALDH1A1TSHRMAPK1SMN1; SMN2HRH3
SCHEMBL2918327 0.81 ALDH1A1 (0.60) ALDH1A1TSHRMAPK1SMN1; SMN2HRH3
SCHEMBL3677741 0.81 ALDH1A1 (0.60) ALDH1A1TSHRMAPK1SMN1; SMN2HRH3
SCHEMBL10941442 0.81 ALDH1A1 (0.72) ALDH1A1TSHRMAPK1SMN1; SMN2HRH3
SCHEMBL10940747 0.81 SMN1; SMN2 (0.72) ALDH1A1TSHRMAPK1SMN1; SMN2HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160231658-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMING APPARATUS Konica Minolta, Inc. (JP) 2016-08-11 US disclosed
US-8962226-B2 Organic photoreceptor, image forming apparatus, and process cartridge Konica Minolta, Inc. (JP) 2015-02-24 US disclosed
US-8889325-B2 Organic photoreceptor Konica Minolta, Inc. (JP) 2014-11-18 US disclosed
US-8404417-B2 Organic photoreceptor, image forming apparatus and process cartridge KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2013-03-26 US disclosed
US-8318396-B2 Organic photoreceptor and preparation method thereof KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2012-11-27 US disclosed
US-8298735-B2 Organic photoreceptor and manufacturing method thereof KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2012-10-30 US disclosed
US-20110217651-A1 IMAGE FORMATION METHOD AND IMAGE FORMATION APPARATUS KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-09-08 US disclosed
US-20110076603-A1 ORGANIC PHOTORECEPTOR, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-03-31 US disclosed
US-20110045391-A1 ORGANIC PHOTORECEPTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-02-24 US disclosed
US-20110045393-A1 ORGANIC PHOTORECEPTOR AND MANUFACTURING METHOD THEREOF KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-02-24 US disclosed
US-20110039197-A1 ORGANIC PHOTORECEPTOR AND PREPARATION METHOD THEREOF KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-02-17 US disclosed
US-20110033204-A1 Organic Photoreceptor, Image Forming Apparatus and Process Cartridge Konica Minolta, Inc. (JP) 2011-02-10 US disclosed